Postmenopausal mild hirsutism and hyperandrogenemia due to ovarian Sertoli-Leydig cell tumor: A case report
| Autor: | Xiang-Hong Wang, Jing Zhang, Shi-Wei Zhang, Dan Chen, Wei Shi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty endocrine system Urology Adnexal mass Article Vulva 03 medical and health sciences 0302 clinical medicine Endocrinology Endocrine system medicine lcsh:Social sciences (General) lcsh:Science (General) Sertoli-Leydig Cell Tumor hirsutism Nutrition Multidisciplinary Hyperandrogenemiai Sertoli-Leydig cell tumor business.industry medicine.disease Metabolic disorder Menopause 030104 developmental biology medicine.anatomical_structure Metabolism Hirsutismi Abdomen lcsh:H1-99 business Body mass index 030217 neurology & neurosurgery lcsh:Q1-390 |
| Zdroj: | Heliyon, Vol 6, Iss 4, Pp e03746-(2020) Heliyon |
| ISSN: | 2405-8440 |
| Popis: | Among several types of ovarian tumors, Sertoli-Leydig cell tumors are considered significantly rare, accounting for less than 1% of all primary ovarian tumors. Hirsutism caused by ovarian tumors accounts for approximately 1% of all cases of hirsutism. We report a case of a woman with a ovarian Sertoli-Leydig cell tumor who presented with hirsutism. A 45-year-old woman (gravida 12, para 2) who experienced menopause when she was 43 years old had excessive hair on her face and lower abdomen since 2 years. Her body mass index was 24.3 kg/m2. She also had hair growth on her upper lip, submandibular area, lower abdomen, vulva, and bilateral tibia (front), and around her breast. She had a Ferriman–Gallwey score of 8. Ultrasound findings revealed a 4.8 × 3.5-cm left adnexal mass. Pelvic computed tomography (CT) findings revealed that her left accessory gland had a low-density mass (CT value, 25 Hu). Her serum testosterone level was 15.80 nmol/l. The patient underwent a laparoscopic left adnexectomy. Subsequently, she was diagnosed with ovarian Sertoli-Leydig cell tumor by immunohistochemical staining. A week after surgery, her serum testosterone level decreased from 15.80 nmol/l to 1.03 nmol/L. Her hirsutism almost completely disappeared 3 months after surgery. It is vitally important to establish the final diagnosis according to the clinical manifestations and laboratory values in addition to imaging studies and laparoscopic examination of a rare coexistence of hirsutism and hyperandrogenemia in a postmenopausal woman based on ovarian pathology. Endocrinology; Endocrine system; Metabolism; Metabolic disorder; Nutrition; Hirsutismi; Hyperandrogenemiai; Sertoli-Leydig cell tumor. |
| Databáze: | OpenAIRE |
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