Dosimetric and physical comparison of IMRT and CyberKnife plans in the treatment of localized prostate cancer
| Autor: | Hande Bas Ayata, N. Kucuk, Kayihan Engin, Metin Güden, C. Ceylan |
|---|---|
| Jazyk: | angličtina |
| Předmět: |
Cancer Research
business.industry Radiography medicine.medical_treatment Prostate CyberKnife Rectum medicine.disease Radiosurgery Radiation therapy Prostate cancer medicine.anatomical_structure Oncology Radiology Nuclear Medicine and imaging Cyberknife Medicine Original Article Radiology Nuclear Medicine and imaging IMRT business Nuclear medicine Fiducial marker |
| Zdroj: | Reports of Practical Oncology & Radiotherapy. (6):181-189 |
| ISSN: | 1507-1367 |
| DOI: | 10.1016/j.rpor.2010.10.003 |
| Popis: | AimThe aim of our study was the dosimetric and physical evaluation of the CK and IMRT treatment plans for 16 patients with localized prostate cancer.BackgroundIntensity modulated radiation therapy (IMRT) is one of the recent technical advances in radiotherapy. The prostate is a well suited site to be treated with IMRT. The challenge of accurately delivering the IMRT needs to be supported by new advances such as image-guidance and four-dimensional computed conformal radiation therapy (4DCRT) tomography. CyberKnife (CK) provides real time orthogonal X-ray imaging of the patient during treatment course to follow gold fiducials installed into the prostate and to achieve motion correlation between online acquired X-ray imaging and digital reconstructed radiographs (DRRs) which are obtained from planning computed tomography images by translating and rotating the treatment table in five directions.Methods and materialsSixteen IMRT and CK plans were performed to be compared in terms of conformity (CI), heterogeneity indices (HI), percentage doses of 100% (V100), 66% (V66), 50% (V50), 33% (V33) and 10% (V10) volumes of the bladder and rectum. Dose-volume histograms for target and critical organs, (CI) and indices (HI) and isodose lines were analyzed to evaluate the treatment plans.ResultsStatistically significant differences in the percentage rectal doses delivered to V10, V33, and V50 of the rectum were detected in favor of the CK plans (p values |
| Databáze: | OpenAIRE |
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