Effect of Thyrotropin-Releasing Hormone (TRH) upon the Menstrual Cycle in Women
| Autor: | Raymond L. Vande Wiele, Andrew G. Frantz, Michelle Warren, Inge Dyrenfurth, Raphael Jewelewicz |
|---|---|
| Rok vydání: | 1974 |
| Předmět: |
endocrine system
medicine.medical_specialty Endocrinology Diabetes and Metabolism media_common.quotation_subject Clinical Biochemistry Thyrotropin-releasing hormone Luteal phase Biochemistry Follicle-stimulating hormone Endocrinology Oral administration Internal medicine medicine Endocrine system Normal range Menstrual cycle media_common business.industry Biochemistry (medical) Obstetrics and Gynecology General Medicine Prolactin Discontinuation Luteinizing hormone business hormones hormone substitutes and hormone antagonists Hormone |
| Zdroj: | The Journal of Clinical Endocrinology & Metabolism. 39:387-390 |
| ISSN: | 1945-7197 0021-972X |
| Popis: | The effect of oral administration of TRH on plasma LH, FSH, estrogens, progesterone and prolactin was studied in six cycles. Forty mg TRH given daily throughout the cycle to one subject did not block the LH surge, but produced a significant depression of progesterone levels. When the same dose was given during the luteal phase only, progesterone levels significantly decreased in 2 women but in 2 others they remained within the normal range. FSH and LH, estrogens and prolactin remained within the normal range in all subjects. One woman developed side effects which prompted discontinuation of TRH. |
| Databáze: | OpenAIRE |
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