Evaluation of antibacterial activity of fruit extracts of Terminalia chebula against Human Pathogenic Bacteria

Autor: Kadudula Prasuna, Yalavarthy Prameela Devi
Jazyk: angličtina
Rok vydání: 2022
Předmět:
DOI: 10.5281/zenodo.7350925
Popis: Terminalia chebula, belongs to a family Combretaceae, is a native of South Asia. The fruit of this plant is one among triphala of ayurveda. This tribal medicine is used to treat for various diseases like throat infections, cellulitis, ear infections and oral infections which are caused by microorganisms. Antibacterial activities of Terminalia chebula extracts against several bacterial strains have been reported. The objective of the present study was to evaluate the possible antimicrobial potential of Terminalia chebula fruit extracts in acetone, ethanol, methanol and water against five streptococci bacteria. Five bacteria i.e., Escherichia coli, Pseudomonas aeruginosa, Shigella boydii, Staphylococcus aureus and Streptococcus faecalis were tested using blood agar as the medium by agar well diffusion and microdilution method. Only methanol extracts showed antibacterial activity against all five species. The highest activity was shown by the methanol extract with a mean diameter of inhibition zone being 14 mm and a minimum inhibitory concentration (MIC) of 1 mg/ml against E. coli followed by S. boydii and S. fascalis. These promising findings suggest the presence of antibacterial activity in the tested plant material, exhibited by its bioactive compounds and serving them as an alternative antimicrobial agent against the tested microorganisms. Keywords: Antibacterial activity, Terminalia chebula, S. boydii, S. fascalis, S. aureus, S. faecalis, P. aeruginosa REFERENCES Afzalakhtar M, Rabber-Bhatti MH, Aslam M (1997). Antibacterial activity of plant Diffusate against Xanthomonas compestris pv. citri. Int. J. Pest Manage. 43(2):149-153. Bauer AW, Kirby WMM, Sherris JC, Turk M (1966). Antibiotic susceptibility testing by a standardized single disk method. Am. J. Clin. Pathol. 45:493-496. Beusher N, Bodinet C, Neumann-Haefelin D, Marston A, Hostettmann K (1994). 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