The effect of cannabis on urge incontinence in patients with multiple sclerosis: a multicentre, randomised placebo-controlled trial (CAMS-LUTS)
| Autor: | M. Waterfield, Ann Waterfield, Robert Freeman, John Zajicek, David Wright, O. A. Adekanmi |
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| Rok vydání: | 2005 |
| Předmět: |
medicine.medical_specialty
Multiple Sclerosis Urology Placebo-controlled study Urination Urinary incontinence Comorbidity Placebo law.invention Randomized controlled trial law Internal medicine medicine Cannabidiol Humans Spasticity Dronabinol biology business.industry Cannabinoids Obstetrics and Gynecology Urinary Incontinence Urge Analgesics Non-Narcotic Middle Aged medicine.disease biology.organism_classification Urodynamics Anesthesia Quality of Life Female Cannabis medicine.symptom business medicine.drug |
| Zdroj: | International urogynecology journal and pelvic floor dysfunction. 17(6) |
| Popis: | Objective: To test whether cannabinoids reduce urge incontinence episodes without affecting voiding in patients with multiple sclerosis. This was part of the multicentre trial of the Cannabinoids in Multiple Sclerosis (CAMS) study. Subjects and methods: The CAMS study randomised 630 patients to receive oral administration of cannabis extract, Δ9-tetrahydrocannabinol (THC) or matched placebo. For this substudy subjects completed incontinence diaries. Results: All three groups showed a significant reduction, p |
| Databáze: | OpenAIRE |
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