Toxoplasmosis Presenting as Nonhealing Cutaneous Ulcer
Autor: | U Rai, S Bhattarai, Sushil Dhakal, M. K. Adhikari |
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Rok vydání: | 2020 |
Předmět: |
Pathology
medicine.medical_specialty Case Report Periodic acid–Schiff stain Lesion 03 medical and health sciences 0302 clinical medicine Dermis medicine RB1-214 Outpatient clinic Abscess biology business.industry Toxoplasma gondii General Medicine medicine.disease biology.organism_classification Toxoplasmosis medicine.anatomical_structure Giant cell 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology medicine.symptom business |
Zdroj: | Case Reports in Pathology Case Reports in Pathology, Vol 2020 (2020) |
ISSN: | 2090-679X 2090-6781 |
DOI: | 10.1155/2020/8874800 |
Popis: | Introduction. Systemic manifestation of toxoplasmosis is commonly seen in immune-compromised individuals. Skin manifestations are seen commonly in conjunction with systemic features. Isolated cutaneous toxoplasmosis is extraordinarily rare in immunocompetent patients. Case Description. A 64-year-old female presented to the Dermatology Outpatient Department (OPD), with a nonhealing ulcer over dorsum of the left hand for one year. The patient did not have any systemic diseases. Serology tests were negative. An incisional biopsy of the lesion revealed dense inflammatory cell infiltrates comprising predominantly of plasma cells and lymphocytes, multinucleated giant cells, and focal abscess formation in the dermis. Periodic Acid Schiff (PAS) stain showed organisms in the dermis with morphological resemblance to tachyzoites of Toxoplasma gondii. Conclusion. Though rare, a possibility of primary cutaneous toxoplasmosis should always be considered and looked for, even in immunocompetent patients presenting with chronic nonhealing ulcers. |
Databáze: | OpenAIRE |
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