Helicobacter Pylori Treatment in Turkey: Current Status and Rational Treatment Options
| Autor: | Mustafa Kaplan, Tolga Duzenli, Ayse Nurdan Tozun, Alpaslan Tanoglu |
|---|---|
| Přispěvatelé: | Acibadem University Dspace |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Turkey medicine.drug_class helicobacter pylori proton pump inhibitors turkey lcsh:Medicine Proton-pump inhibitor Review CYP2C19 03 medical and health sciences 0302 clinical medicine Antibiotic resistance Internal medicine Medicine Eradication lcsh:R5-920 Helicobacter pylori biology business.industry Fda approval lcsh:R Clarithromycin 500 MG Treatment options Amoxicillin biology.organism_classification 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology lcsh:Medicine (General) business General Economics Econometrics and Finance medicine.drug |
| Zdroj: | Northern Clinics of Istanbul İstanbul Kuzey Klinikleri, Vol 7, Iss 1, Pp 87-94 (2020) |
| ISSN: | 2148-4902 |
| DOI: | 10.14744/nci.2019.62558 |
| Popis: | According to the TURHEP study, the prevalence of Helicobacter pylori in Turkey is 82.5%. After FDA approval in 1995, many countries have used standard triple therapy (proton pump inhibitor 40 mg b.i.d clarithromycin 500 mg b.i.d and amoxicillin 1 gr b.i.d) for Helicobacter pylori treatment. In the beginning, eradication rates were above 90% in many countries; however, current studies have demonstrated a prominent decrease in successful treatment rates, even down to 60%. This unfavorable reduction stimulated searches for new treatment protocols. Treatment protocols differ according to country, prevalence, cost-effectiveness, antibiotic resistance, CYP2C19 polymorphism and eradication rates. Thus, each country/region needs to revise its own therapeutic results and the efficacy of various eradication regimens in the treatment of Helicobacter pylori. This report aims to review the current status of Helicobacter pylori treatment in Turkey and to provide recommendations for rational therapeutic considerations for the eradication of the bacterium. (NCI-2019-0024.R1) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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