Pregnancy and birth after intracytoplasmic sperm injection of in vitro matured germinal-vesicle stage oocytes
Autor: | Z. Nagy, Janssenwillen Cecile, Andre Van Steirteghem, Paul Devroey, Ann Loccufier, Jiaen Liu |
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Přispěvatelé: | Department of Embryology and Genetics, Centre for Reproductive Medicine - Gynaecology |
Jazyk: | angličtina |
Rok vydání: | 1996 |
Předmět: |
Adult
Male Cytoplasm Microinjections medicine.medical_treatment Fertilization in Vitro Biology Intracytoplasmic sperm injection Andrology Human fertilization Ovulation Induction Pregnancy Culture Techniques medicine Humans Microinjection Infertility Male Germinal vesicle Embryogenesis Pregnancy Outcome Obstetrics and Gynecology medicine.disease Oocyte Embryo Transfer In vitro maturation medicine.anatomical_structure Reproductive Medicine Oocytes Female |
DOI: | 10.1016/s0015-0282(16)58285-5 |
Popis: | Objective: To report a normal pregnancy and the delivery of a healthy child after the combination of in vitro maturation of germinal-vesicle stage oocytes and intracytoplasmic sperm injection (ICSI) in a patient. Setting: Procedures were performed in a tertiary IVF center coupled with an institutional research environment. Main Outcome Measures: Maturation rate of immature oocytes after in vitro maturation and intactness, fertilization, and developmental rates of oocytes after microinjection. Results: Nine of 14 germinal-vesicle stage oocytes matured to the metaphase II stage after 30 hours of in vitro culture (64%). Seven of eight injected and intact oocytes fertilized normally (78%) and five of them cleaved with |
Databáze: | OpenAIRE |
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