Pregnancy and birth after intracytoplasmic sperm injection of in vitro matured germinal-vesicle stage oocytes

Autor: Z. Nagy, Janssenwillen Cecile, Andre Van Steirteghem, Paul Devroey, Ann Loccufier, Jiaen Liu
Přispěvatelé: Department of Embryology and Genetics, Centre for Reproductive Medicine - Gynaecology
Jazyk: angličtina
Rok vydání: 1996
Předmět:
DOI: 10.1016/s0015-0282(16)58285-5
Popis: Objective: To report a normal pregnancy and the delivery of a healthy child after the combination of in vitro maturation of germinal-vesicle stage oocytes and intracytoplasmic sperm injection (ICSI) in a patient. Setting: Procedures were performed in a tertiary IVF center coupled with an institutional research environment. Main Outcome Measures: Maturation rate of immature oocytes after in vitro maturation and intactness, fertilization, and developmental rates of oocytes after microinjection. Results: Nine of 14 germinal-vesicle stage oocytes matured to the metaphase II stage after 30 hours of in vitro culture (64%). Seven of eight injected and intact oocytes fertilized normally (78%) and five of them cleaved with
Databáze: OpenAIRE