Acute ischemic optic nerve disease: Pathophysiology, clinical features and management
| Autor: | E. Héron, Christophe Baudouin, Edouard Augstburger, A. Abanou, Antoine Labbé, Christophe Habas |
|---|---|
| Přispěvatelé: | Institut de la Vision, Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Versailles Saint-Quentin-en-Yvelines - UFR Sciences de la santé Simone Veil (UVSQ Santé), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Service d'ophtalmologie [CHU Ambroise Paré], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Ambroise Paré [AP-HP] |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
[SDV]Life Sciences [q-bio] Giant Cell Arteritis Vision Disorders Context (language use) Disease Drusen Blindness 03 medical and health sciences 0302 clinical medicine medicine Humans Optic Neuropathy Ischemic Age of Onset Intensive care medicine Aged Aged 80 and over Vascular disease business.industry Middle Aged Ischemic optic neuropathy medicine.disease 3. Good health Ophthalmology Giant cell arteritis Acute Disease 030221 ophthalmology & optometry Optic nerve Etiology business |
| Zdroj: | Journal Français D'Ophtalmologie Journal Français D'Ophtalmologie, Elsevier Masson, 2020, 43, pp.e41-e54. ⟨10.1016/j.jfo.2019.12.002⟩ |
| ISSN: | 0181-5512 |
| Popis: | Ischemic optic neuropathies are among the leading causes of severe visual acuity loss in people over 50 years of age. They constitute a set of various entities that are clinically, etiologically and therapeutically different. Anatomically, it is necessary to distinguish anterior and posterior forms. From an etiological point of view, the diagnosis of the arteritic form due to giant cell arteritis requires emergent management to prevent blindness and even death in the absence of prompt corticosteroid treatment. When this diagnosis has been ruled out with certainty, non-arteritic ischemic optic neuropathies represent a vast etiological context that in the majority of cases involves a local predisposing factor (small optic nerves, disc drusen) with a precipitating factor (severe hypotension, general anesthesia or dialysis) in a context of vascular disease (sleep apnea syndrome, hypertension, diabetes, etc.). In the absence of specific available treatment, it is the responsibility of the clinician to identify the risk factors involved, in order to reduce the risk of contralateral recurrence that may occur even several years later. Due to their complexity, these pathologies are the subject of debates regarding both the pathophysiological and therapeutic perspectives; this review aims to provide a synthesis of validated knowledge while discussing controversial data. |
| Databáze: | OpenAIRE |
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