Effectiveness and Infant Acceptance of the Rx Medibottle versus the Oral Syringe
| Autor: | Patricia R. Hannon, Donna M. Kraus, Sally Freels, Leslie A. Stohlmeyer |
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| Rok vydání: | 2001 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Administration Oral law.invention Infant Equipment Patient satisfaction Randomized controlled trial law Oral administration Humans Medicine Outpatient clinic Pharmacology (medical) Prospective Studies Prospective cohort study Syringe Acetaminophen Cross-Over Studies business.industry Syringes Infant Equipment Design Analgesics Non-Narcotic Crossover study Bottle Feeding Patient Satisfaction Female business |
| Zdroj: | Pharmacotherapy: Official Journal of the American College of Clinical Pharmacy. 21:416-423 |
| ISSN: | 0277-0008 |
| Popis: | Study Objective. To compare the effectiveness and infant acceptance of drug delivery of the Rx medibottle with the standard oral syringe. Design. Prospective open-label, randomized, crossover clinical study. Setting. General pediatric outpatient clinic at an urban university. Subjects. Thirty healthy, bottle-fed infants, aged 2–14 months, receiving routine vaccinations. Intervention. Each infant received a single dose of acetaminophen (Tempra syrup), with one-half delivered by the Rx medibottle and one-half delivered with an oral syringe. Measurements and Main Results. Three raters independently evaluated effectiveness and infant acceptance of each drug-delivery device. Effectiveness was based on the percentage of infants receiving 100% of the intended dose. Infant acceptance was scored using a validated infant medication acceptance scale (MAS, 10 = highest level). Significantly more infants received 100% of the intended dose with the Rx medibottle (93.3%) than with the oral syringe (56.7%, p=0.0074). Infants had a significantly higher mean MAS score when using the Rx medibottle (8.3 ± 1.8 vs 7.3 ± 1.7, p=0.002). In addition, a significantly higher percentage had ideal MAS scores of 9 or above with the Rx medibottle (73%) compared with the oral syringe (17%, p=0.0001). Conclusion. The Rx medibottle was more effective and had a higher level of infant acceptance than the oral syringe. Although further studies are necessary, this suggests that the Rx medibottle may be a better method of delivering liquid drug and may increase infant adherence. |
| Databáze: | OpenAIRE |
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