Functional brain changes in the elderly for the perception of hand movements: A greater impairment occurs in proprioception than touch

Autor: Olivier Felician, Julien Sein, Caroline Landelle, Anne Kavounoudias, Bruno Nazarian, Ali Gharbi, Jean-Luc Anton
Přispěvatelé: Neurosciences sensorielles et cognitives (NSC), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Institut de Neurosciences de la Timone (INT), Institut de Neurosciences des Systèmes (INS), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), ANR-12-JSH2-0005,Multisense,Intégration multisensorielle et perception kinesthesique : corrélats cérébraux, modélisation Bayésienne et plasticité adaptative liée au vieillissement(2012), ANR-11-IDEX-0001,Amidex,INITIATIVE D'EXCELLENCE AIX MARSEILLE UNIVERSITE(2011), ANR-11-INBS-0006,FLI,France Life Imaging(2011), Kavounoudias, Anne, Jeunes Chercheuses et Jeunes Chercheurs - Intégration multisensorielle et perception kinesthesique : corrélats cérébraux, modélisation Bayésienne et plasticité adaptative liée au vieillissement - - Multisense2012 - ANR-12-JSH2-0005 - JC - VALID, INITIATIVE D'EXCELLENCE AIX MARSEILLE UNIVERSITE - - Amidex2011 - ANR-11-IDEX-0001 - IDEX - VALID, Infrastructures - France Life Imaging - - FLI2011 - ANR-11-INBS-0006 - INBS - VALID
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Adult
Male
medicine.medical_specialty
Cognitive Neuroscience
media_common.quotation_subject
Movement
Illusion
Motion Perception
Audiology
Somatosensory system
050105 experimental psychology
lcsh:RC321-571
Resting-state
03 medical and health sciences
Young Adult
0302 clinical medicine
Tactile illusions
Perception
medicine
Humans
0501 psychology and cognitive sciences
Sensorimotor network
Kinesthesis
lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry
Balance (ability)
media_common
Aged
Sensory stimulation therapy
Resting state fMRI
Proprioception
[SCCO.NEUR]Cognitive science/Neuroscience
[SCCO.NEUR] Cognitive science/Neuroscience
05 social sciences
fMRI
Hand
Magnetic Resonance Imaging
Neurology
Touch Perception
Kinesthesia
Touch
Aging brain
Female
Sensorimotor Cortex
Psychology
030217 neurology & neurosurgery
Zdroj: NeuroImage
NeuroImage, 2020, 220, pp.117056. ⟨10.1016/j.neuroimage.2020.117056⟩
NeuroImage, Vol 220, Iss, Pp 117056-(2020)
NeuroImage, Elsevier, 2020, 220, pp.117056. ⟨10.1016/j.neuroimage.2020.117056⟩
ISSN: 1053-8119
1095-9572
DOI: 10.1016/j.neuroimage.2020.117056⟩
Popis: International audience; Unlike age-related brain changes linked to motor activity, neural alterations related to self-motion perception remain unknown. Using fMRI data, we investigated age-related changes in the central processing of somatosensory information by inducing illusions of right-hand rotations with specific proprioceptive and tactile stimulation. Functional connectivity during resting-state (rs-FC) was also compared between younger and older participants. Results showed common sensorimotor activations in younger and older adults during proprioceptive and tactile illusions, but less deactivation in various right frontal regions and the precuneus were found in the elderly. Older participants exhibited a less-lateralized pattern of activity across the primary sensorimotor cortices (SM1) in the proprioceptive condition only. This alteration of the interhemispheric balance correlated with declining individual performance in illusion velocity perception from a proprioceptive, but not a tactile, origin. By combining task-related data, rs-FC and behavioral performance, this study provided consistent results showing that hand movement perception was altered in the elderly, with a more pronounced deterioration of the proprioceptive system, likely due to the breakdown of inhibitory processes with aging. Nevertheless, older people could benefit from an increase in internetwork connectivity to overcome this kinesthetic decline.
Databáze: OpenAIRE
Externí odkaz: