Association between fat mass index, fat‐free mass index and hemoglobin A1c in a Japanese population: The Tohoku Medical Megabank Community‐based Cohort Study
Autor: | Masato Takase, Yohei Hamanaka, Eiichi Kodama, Kichiya Suzuki, Takumi Hirata, Shigeo Kure, Junichi Sugawara, Fumi Itabashi, Naoki Nakaya, Nobuo Fuse, Shinichi Kuriyama, Ichiro Tsuji, Naho Tsuchiya, Uruno Akira, Tomohiro Nakamura, Atsushi Hozawa, Mana Kogure |
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Rok vydání: | 2021 |
Předmět: |
Blood Glucose
Male Index (economics) Endocrinology Diabetes and Metabolism Body Mass Index Cohort Studies Japan Fat free mass Diabetes mellitus Internal Medicine Humans Medicine Mass index Glycated Hemoglobin business.industry Regression analysis General Medicine medicine.disease Cross-Sectional Studies Adipose Tissue Quartile Female Hemoglobin business Cohort study Demography |
Zdroj: | Journal of Diabetes Investigation. 13:858-867 |
ISSN: | 2040-1124 2040-1116 |
Popis: | AIMS/INTRODUCTION Fat mass and fat-free mass affect glycated hemoglobin A1c (HbA1c) levels and blood glucose levels, respectively. The aim of the present study was to examine the association between fat mass index and fat-free mass index with HbA1c. MATERIALS AND METHODS We conducted a cross-sectional study that included 3,731 men and 9,191 women aged 20 years or older, living in Miyagi Prefecture, Japan, who were not treated for diabetes. The fat mass index and fat-free mass index were calculated as fat mass and fat-free mass divided by the height squared, respectively. The indices were classified into sex-specific quartiles and combined into 16 groups. An ANCOVA was used to assess associations between the combined fat mass index and fat-free mass index with HbA1c adjusted for potential confounder. The linear trend test was conducted by stratifying the fat mass index and fat free mass index, entering the number as a continuous term in the regression model. RESULTS In multivariable models, a higher fat mass index was related to higher HbA1c levels in men and women in all fat-free mass index subgroups (P |
Databáze: | OpenAIRE |
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