Osteoclast-like giant cell tumour of the pancreas presenting as a pseudocyst-like lesion
| Autor: | Matthias Jürs, Burkhard Helpap, Ulrich Oehler, Günter Klöppel |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Male
Pathology medicine.medical_specialty Pancreatic disease Vimentin Biology Pathology and Forensic Medicine Diagnosis Differential Lesion Cytokeratin Fatal Outcome Pancreatic Pseudocyst Biomarkers Tumor medicine Humans Molecular Biology Histiocyte Giant Cell Tumors Osteoclast-Like Giant Cell Nuclear Proteins Antigens Nuclear Cell Biology General Medicine Middle Aged medicine.disease Immunohistochemistry digestive system diseases Pancreatic Neoplasms Jejunum Ki-67 Antigen medicine.anatomical_structure Giant cell biology.protein Keratins Neoplasm Recurrence Local medicine.symptom Pancreas |
| Zdroj: | Virchows Archiv. 431:215-218 |
| ISSN: | 1432-2307 0945-6317 |
| DOI: | 10.1007/s004280050091 |
| Popis: | A 57-year-old male patient presented with a cystic lesion in the tail of the pancreas, which was considered to be a pseudocyst. He was treated by cystojejunostomy but one year later a tumour was found to have invaded the stomach and jejunum. This was an osteoclast-like giant cell tumour containing a small area of typical ductal adenocarcinoma. Immunohistochemical staining revealed that the pleomorphic tumour cells were positive for cytokeratin, epithelial membrane antigen, vimentin and the proliferation marker MIB-1. The osteoclast-like giant cells and some small histiocytic cells stained for leukocyte common antigen and histiocytic markers and were negative for MIB-1. At autopsy, tumour rests were found in the pancreas but there were no metastases. Osteoclast-like giant cell tumours of the pancreas may present as cystic lesions and should be included in the differential diagnosis of pseudocysts. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink