Risks of cardio-vascular diseases among highly active antiretroviral therapy (HAART) treated HIV seropositive volunteers at a treatment centre in Lagos, Nigeria
| Autor: | D Oladele, Oloruntoba Ayodele Ekun, Gideon Odemakpore Liboro, T. Y. Raheem, Emmanuel Olusesan Fasela |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty cardiac risk ratio Anti-HIV Agents Cross-sectional study Nigeria HIV Infections Disease Sex Factors Risk Factors Antiretroviral Therapy Highly Active Internal medicine medicine Humans Framingham Risk Score medicine.diagnostic_test business.industry Research dyslipidemia Age Factors virus diseases QRISK3 General Medicine Middle Aged highly active antiretroviral therapy medicine.disease Cardiovascular disease CD4 Lymphocyte Count Cross-Sectional Studies Blood pressure Cardiovascular Diseases Female Kidney Diseases Lipid profile business Body mass index Viral load Dyslipidemia cardiac risk ratio (CRR) |
| Zdroj: | The Pan African Medical Journal Pan African Medical Journal; Vol. 38 No. 1 (2021) |
| ISSN: | 1937-8688 |
| Popis: | Introduction:highly active antiretroviral therapy (HAART) has led to a decline in HIV-induced morbidity and mortality in recent years. However, it has been opined that this has led to elevated risks of cardiovascular diseases (CVDs). This study assessed the risks of CVDs among HAART experienced individuals living with HIV. Methods:a cross sectional study involving 196 adults consisting of 118 HAART experienced and 78 HAART naïve was conducted. Anthropometric and blood pressure measurements were recorded for all participants. Blood samples obtained from the volunteers were used to determine glucose, creatinine, HIV viral load, CD4 count and lipid profile using standard methods. Lipid ratios, atherogenic indices and QRISK3 risk score were calculated. Results:the median CD4 lymphocyte, mean body mass index (BMI) and HDL-c in HAART experienced participants were higher (P45 years) volunteers. The risk of renal disease appeared higher in females. |
| Databáze: | OpenAIRE |
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