Alexithymia and Cardiac Outcome in Patients at First Acute Coronary Syndrome

Autor:	Carlo Marchesi, Marco Beltrani, Maria Lidia Gerra, Paolo Ossola
Rok vydání:	2019
Předmět:	Adult Male medicine.medical_specialty Acute coronary syndrome Coronary artery disease Cohort Studies 03 medical and health sciences Toronto Alexithymia Scale 0302 clinical medicine Alexithymia Recurrence Risk Factors Internal medicine medicine Humans 030212 general & internal medicine Affective Symptoms Risk factor Acute Coronary Syndrome Applied Psychology Depression (differential diagnoses) Proportional Hazards Models 030505 public health medicine.diagnostic_test business.industry Proportional hazards model Depression Middle Aged medicine.disease Female 0305 other medical science business Mace Follow-Up Studies
Zdroj:	International journal of behavioral medicine. 26(6)
ISSN:	1532-7558
Popis:	This cohort study was aimed to verify whether subjects at their first acute coronary syndrome (ACS) were more alexithymic than healthy controls (HC) and whether alexithymia can predispose patients with coronary artery disease to new major adverse cardiac events (MACE) during a 24-month follow-up period. The sample included 100 HC with no history of depression or ACS and 304 never depressed patients with a first-ever ACS. A total of 266 patients completed the 2-year follow-up. Patients and HC reported similar Toronto Alexithymia Scale (TAS-20) scores. During the follow-up, 69 (22.69%) patients developed incident depression and 57 (18.75%) developed a new MACE. In a proportional hazard model, developing a first-ever depressive episode, but not alexithymia (hazard ratio = 1.008, 95% confidence interval = 0.984–1.033; p = 0.500), was associated with almost 3 times the risk of a recurrent cardiac event. Incident depression, but not TAS-20 scores, represented risk factor for MACE.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0848fc8a070b7286647b3cdb2b5f1b01 https://pubmed.ncbi.nlm.nih.gov/31745728 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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