Limited Liver or Lung Colorectal Cancer Metastases. Systemic Treatment, Surgery, Ablation or SBRT
Autor: | Molla, Meritxell, Fernandez-Plana, Julen, Albiol, Santiago, Fondevila, Constantino, Vollmer, Ivan, Cases, Carla, García-Criado, A., Capdevila Castillón, Jaume, Conill, Carles, Fundora, Yliam, Fernández-Martos, Carlos, Pineda, Estela, Universitat Autònoma de Barcelona |
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Přispěvatelé: | Institut Català de la Salut, [Molla M] Department of Radiation Oncology, Hospital Clinic Barcelona, Barcelona 08036, Spain. Translational Genomics and Targeted Therapeutics in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona 08036, Spain. [Fernandez-Plana J] Department of Medical Oncology, Hospital Mutua de Terrassa, Terrassa 08221, Spain. [Albiol S] Department of Medical Oncology, Hospital Clinic de Barcelona, Barcelona 08036, Spain. [Fondevila C] Department of General and Digestive Surgery, Hospital Clinic de Barcelona, Barcelona 08036, Spain. [Vollmer I] Department of Radiology, Hospital Clinic Barcelona, Barcelona 08036, Spain. [Cases C] Department of Radiation Oncology, Hospital Clinic Barcelona, Barcelona 08036, Spain. [Capdevila J] Servei d’Oncologia Mèdica, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain, Vall d'Hebron Barcelona Hospital Campus |
Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Oncology
medicine.medical_specialty Percutaneous Stereotactic body radiation therapy Colorectal cancer medicine.medical_treatment colorectal cancer Review Ablation stereotactic body radiation therapy ablation 030218 nuclear medicine & medical imaging Liver metastases Còlon - Càncer - Tractament 03 medical and health sciences Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal Neoplasms::Colorectal Neoplasms [DISEASES] 0302 clinical medicine Metàstasi Internal medicine Recte - Càncer - Tractament medicine In patient Otros calificadores::/terapia [Otros calificadores] Oligometastasis Lung business.industry Neoplasms::Neoplastic Processes::Neoplasm Metastasis [DISEASES] lung metastases Other subheadings::/therapy [Other subheadings] General Medicine neoplasias::neoplasias por localización::neoplasias del sistema digestivo::neoplasias gastrointestinales::neoplasias intestinales::neoplasias colorrectales [ENFERMEDADES] medicine.disease oligometastasis medicine.anatomical_structure neoplasias::procesos neoplásicos::metástasis neoplásica [ENFERMEDADES] 030220 oncology & carcinogenesis Treatment surgery RAS Mutation Medicine business liver metastases Lung metastases |
Zdroj: | Journal of Clinical Medicine, Vol 10, Iss 2131, p 2131 (2021) Scientia Dipòsit Digital de Documents de la UAB Universitat Autònoma de Barcelona Journal of Clinical Medicine |
ISSN: | 2077-0383 |
Popis: | Ablació; Càncer colorectal; Metàstasis del fetge Ablación; Cáncer colorrectal; Metástasis en el hígado Ablation; Colorectal cancer; Liver metastases The prognosis for oligometastatic colorectal cancer has improved in recent years, mostly because of recent advances in new techniques and approaches to the treatment of oligometastases, including new surgical procedures, better systemic treatments, percutaneous ablation, and stereotactic body radiation therapy (SBRT). There are several factors to consider when deciding on the better approach for each patient: tumor factors (metachronous or synchronous metastases, RAS mutation, BRAF mutation, disease-free interval, size and number of metastases), patient factors (age, frailty, comorbidities, patient preferences), and physicians’ factors (local expertise). These advances have presented major challenges and opportunities for oncologic multidisciplinary teams to treat patients with limited liver and lung metastases from colorectal cancer with a curative intention. In this review, we describe the different treatment options in patients with limited liver and lung metastases from colorectal cancer, and the possible combination of three approaches: systemic treatment, surgery, and local ablative treatments. This research received no external funding. |
Databáze: | OpenAIRE |
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