Controlled Comparison of BacT/Alert MB System, Manual Myco/F Lytic Procedure, and Isolator 10 System for Diagnosis of Mycobacterium tuberculosis Bacteremia
| Autor: | Boniface N. Njau, L B Reller, Anne B. Morrissey, Habib O. Ramadhani, Venance P. Maro, John A. Crump |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Microbiology (medical) Time Factors Tuberculosis Adolescent Bacteremia Sensitivity and Specificity Microbiology Mycobacterium tuberculosis Young Adult fluids and secretions Tuberculosis diagnosis medicine Humans Blood culture Aged Aged 80 and over Bacteriological Techniques biology medicine.diagnostic_test business.industry Bact alert Isolator Mycobacteriology and Aerobic Actinomycetes Middle Aged equipment and supplies bacterial infections and mycoses medicine.disease biology.organism_classification Lytic cycle business |
| Zdroj: | Journal of Clinical Microbiology. 49:3054-3057 |
| ISSN: | 1098-660X 0095-1137 |
| DOI: | 10.1128/jcm.01035-11 |
| Popis: | We compared the performance of the BacT/Alert MB system, that of the manual Bactec Myco/F Lytic procedure, and that of the Isolator 10 lysis-centrifugation system in the detection of Mycobacterium tuberculosis bacteremia. Mean times to detection were 16.4 days for BacT/Alert MB versus 20.0 days for Myco/F Lytic, 16.5 days for BacT/Alert MB versus 23.8 days for Isolator 10, and 21.1 days for Bactec Myco/F Lytic versus 22.7 days for Isolator 10. There were no significant differences in yields. The mean (range) magnitude of mycobacteremia was 30.0 (0.4, 90.0) CFU/ml and was correlated with the time to positivity in the BacT/Alert MB system ( r = −0.4920). M. tuberculosis bacteremia was detected more rapidly in a continuously monitored liquid blood culture system, but the mean time to positivity exceeded 3 weeks. |
| Databáze: | OpenAIRE |
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