LncRNA-599547 contributes the inductive property of dermal papilla cells in cashmere goat through miR-15b-5p/Wnt10b axis

Autor:	Su J. Zhao, Rong L. Yin, Wei Wang, Wen L. Bai, Ze Y Wang, Yi X Fan, Rong H. Yin, Man Bai, Yu B. Zhu
Rok vydání:	2020
Předmět:	integumentary system Goats Bioengineering Biology Hair follicle Cell biology MicroRNAs Dermal papillae medicine.anatomical_structure medicine Cashmere goat Animals Animal Science and Zoology RNA Long Noncoding RNA Messenger Hair Follicle Biotechnology
Zdroj:	Animal biotechnology. 33(3)
ISSN:	1532-2378
Popis:	The lncRNA-599547 (619-nt in length) is identified in secondary hair follicle (SHF) of cashmere goat, but its functional roles in regulating the inductive property of dermal papilla cells (DPCs) remains unknown. We found that lncRNA-599547 had significantly higher expression in dermal papilla of cashmere goat SHF at anagen than its counterpart at telogen. The overexpression of lncRNA-599547 led to a significant increase of ALP and LEF1 expression in DPCs (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08395789649b53eed0d41db3a2b37181 https://pubmed.ncbi.nlm.nih.gov/32808845 Zobrazit plný text záznamu