The Issue of Subclinical Leaflet Thrombosis After Transcatheter Aortic Valve Implantation
| Autor: | Giulio Russo, Sercan Okutucu, Estêvão Carvalho de Campos Martins, Dinaldo Cavalcanti de Oliveira |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Transcatheter aortic genetic structures Computed tomography Review 030204 cardiovascular system & hematology Subclinical leaflet thrombosis 03 medical and health sciences 0302 clinical medicine Internal medicine Medicine 030212 general & internal medicine Subclinical infection medicine.diagnostic_test business.industry Aortic stenosis Therapeutic effect medicine.disease Thrombosis Oral anticoagulants Stenosis Dual antiplatelet therapy Cardiology Thickening Cardiology and Cardiovascular Medicine Complication business |
| Zdroj: | Cardiology Research |
| ISSN: | 1923-2829 |
| Popis: | Transcatheter aortic valve implantation (TAVI) has been considered an important therapy for the treatment of symptomatic severe aortic stenosis. Although the devices and the techniques have been improved some complications may occur and several issues still need to be addressed. The issue of subclinical leaflet thrombosis (SLT) has been recognized as a complication after TAVI, and its incidence ranges from 0% to 40%. Nowadays, computed tomography is considered as the standard method for diagnosis of SLT. The concept of hypoattenuated leaflet thickening (HALT), reduced leaflet motion (RELM), and hypoattenuation affecting motion (HAM) have been used in this topic. Most patients who had SLT were taking single or dual antiplatelet therapy. In addition, these medications were not effective in resolving this complication after TAVI. However, there is a suggestion that oral anticoagulants have a protective and therapeutic effect. With the increasing use of TAVI, it is necessary to have better knowledge about several aspects of this complication, because it may have impact on prognosis. Therefore, some aspects of SLT diagnosis, management, and prognosis are not yet fully understood. |
| Databáze: | OpenAIRE |
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