Rationale and Design of the Hamburg City Health Study
| Autor: | Robert Kromer, Eike Sebastian Debus, Klaus Pantel, Jürgen Gallinat, Birgit-Christiane Zyriax, Imke Thederan, Christian Büchel, Simone Gellißen, Lina Nagel, Katrin Borof, Claudia Terschüren, Christian Stephan Betz, Bernd Löwe, Peer Briken, Larissa Eggers, Stefan Blankenberg, Guido Sauter, Götz Thomalla, Elina Petersen, Alexander Konnopka, Olaf von dem Knesebeck, Holger Schulz, Christoph Heidemann, Ulrich Schiffner, Carsten Bokemeyer, Benjamin Waschki, Tanja Zeller, Volker Harth, Karl Wegscheider, Jens Fiehler, Vladislavs Sokalskis, Ralf Smeets, Christoffer Johansen, Martin Scherer, Marvin O Kampf, Tobias B. Huber, Katharina Scherschel, Hans-Helmut König, Martin Gosau, Stefanie Brassen, Sven Anders, Ghazal Aarabi, Martin Härter, Jan-Per Wenzel, Gunnar K. Lund, Klaus Püschel, Sonja Loges, Christoph Busch, Renate B. Schnabel, Albert Nienhaus, Thomas Beikler, Matthias Augustin, Martin S. Spitzer, Uwe Koch-Gromus, Ramona B der Kellen, Tom Thoma, Christian-Alexander Behrendt, Guido Heydecke, Susanne Wiese, Annika Jagodzinski, Christian Gerloff, Markus Graefen, Christian Kubisch, Christian Meyer, Hermann Reichenspurner, Gerhard Adam, Simone Kühn, Evaldas Girdauskas, Yassin Hussein |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
Proteomics adipositas Epidemiology Coronary Artery Disease Survivorship Prospective cohort study Risk factors Coronary heart disease Vascular diseases Oral health Psychiatric and psychosomatic disorders Ocular diseases Respiratory diseases Obesity Sexual dysfunction MRI imaging Cardiac MRI Brain MRI Health service research Mikrozensus Resilienz 0302 clinical medicine Germany Surveys and Questionnaires Health care Medicine Social Medicine Prospective Studies Cancer education.field_of_study Incidence public health longitudinal study Prophylaxe psychische Krankheit Fettsucht Population Surveillance Medicine and health Cohort study medicine.medical_specialty Prognose 03 medical and health sciences Quality of life (healthcare) Hamburg Humans education Life Style Aged Epidemiologie Heart Failure Gesundheitsvorsorge Krebs Resilience Public health Prevention life style Lifestyle Demenz Dementia prognosis 030217 neurology & neurosurgery Lebensstil Ernährung Gerontology Oral Health heart disease Cohort Studies Risk Factors Neoplasms Atrial Fibrillation Prevalence 030212 general & internal medicine risk Mental Disorders health Middle Aged New Study mental illness Magnetic Resonance Imaging Bundesrepublik Deutschland Stroke Research Design Female prophylaxis Herzkrankheit Psychosocial chronic illness Schlaganfall Population Federal Republic of Germany Survivorship curve medicine Risiko ddc:610 chronische Krankheit Nutrition Medizin und Gesundheit business.industry Gesundheitsversorgung Gesundheit Längsschnittuntersuchung Medizin Sozialmedizin Chronic Disease Quality of Life business |
| Zdroj: | European Journal of Epidemiology Jagodzinski, A, Johansen, C, Koch-Gromus, U, Aarabi, G, Adam, G, Anders, S, Augustin, M, der Kellen, R B, Beikler, T, Behrendt, C A, Betz, C S, Bokemeyer, C, Borof, K, Briken, P, Busch, C J, Büchel, C, Brassen, S, Debus, E S, Eggers, L, Fiehler, J, Gallinat, J, Gellißen, S, Gerloff, C, Girdauskas, E, Gosau, M, Graefen, M, Härter, M, Harth, V, Heidemann, C, Heydecke, G, Huber, T B, Hussein, Y, Kampf, M O, von dem Knesebeck, O, Konnopka, A, König, H H, Kromer, R, Kubisch, C, Kühn, S, Loges, S, Löwe, B, Lund, G, Meyer, C, Nagel, L, Nienhaus, A, Pantel, K, Petersen, E, Püschel, K, Reichenspurner, H, Sauter, G, Scherer, M, Scherschel, K, Schiffner, U, Schnabel, R B, Schulz, H, Smeets, R, Sokalskis, V, Spitzer, M S, Terschüren, C, Thederan, I, Thoma, T, Thomalla, G, Waschki, B, Wegscheider, K, Wenzel, J P, Wiese, S, Zyriax, B C, Zeller, T & Blankenberg, S 2020, ' Rationale and Design of the Hamburg City Health Study ', European Journal of Epidemiology, vol. 35, no. 2, pp. 169-181 . https://doi.org/10.1007/s10654-019-00577-4 |
| ISSN: | 1573-7284 |
| Popis: | The Hamburg City Health Study (HCHS) is a large, prospective, long-term, population-based cohort study and a unique research platform and network to obtain substantial knowledge about several important risk and prognostic factors in major chronic diseases. A random sample of 45,000 participants between 45 and 74 years of age from the general population of Hamburg, Germany, are taking part in an extensive baseline assessment at one dedicated study center. Participants undergo 13 validated and 5 novel examinations primarily targeting major organ system function and structures including extensive imaging examinations. The protocol includes validate self-reports via questionnaires regarding lifestyle and environmental conditions, dietary habits, physical condition and activity, sexual dysfunction, professional life, psychosocial context and burden, quality of life, digital media use, occupational, medical and family history as well as healthcare utilization. The assessment is completed by genomic and proteomic characterization. Beyond the identification of classical risk factors for major chronic diseases and survivorship, the core intention is to gather valid prevalence and incidence, and to develop complex models predicting health outcomes based on a multitude of examination data, imaging, biomarker, psychosocial and behavioral assessments. Participants at risk for coronary artery disease, atrial fibrillation, heart failure, stroke and dementia are invited for a visit to conduct an additional MRI examination of either heart or brain. Endpoint assessment of the overall sample will be completed through repeated follow-up examinations and surveys as well as related individual routine data from involved health and pension insurances. The study is targeting the complex relationship between biologic and psychosocial risk and resilience factors, chronic disease, health care use, survivorship and health as well as favorable and bad prognosis within a unique, large-scale long-term assessment with the perspective of further examinations after 6 years in a representative European metropolitan population. Electronic supplementary material The online version of this article (10.1007/s10654-019-00577-4) contains supplementary material, which is available to authorized users. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink