Association between donor-recipient serum sodium differences and orthotopic liver transplant graft function
| Autor: | John J. Fung, Jacek B. Cywinski, Nick Pesa, Joseph P. Vincent, Charles Miller, Bijan Eghtesad, Brian M. Parker, Shunichi Nakagawa, Jie Na, Edward J. Mascha |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Liver transplantation Gastroenterology Liver disease Postoperative Complications Blood product Internal medicine medicine Humans Postoperative Period Survival rate Retrospective Studies Transplantation Hypernatremia Hepatology medicine.diagnostic_test business.industry Graft Survival Sodium Prognosis medicine.disease Tissue Donors Liver Transplantation Surgery Survival Rate Fresh frozen plasma Hyponatremia business Liver function tests Biomarkers Liver Failure Follow-Up Studies |
| Zdroj: | Liver Transplantation. 14:59-65 |
| ISSN: | 1527-6473 1527-6465 |
| DOI: | 10.1002/lt.21305 |
| Popis: | Previous studies have shown that donor hypernatremia and possibly recipient hyponatremia negatively impact graft function after orthotopic liver transplant (OLT). The purpose of this retrospective investigation was to determine whether measured differences in serum sodium values between cadaveric donors and OLT recipients (DeltaNa(+)) influence immediate postoperative allograft function and short-term patient outcomes. Two hundred and fifty patients that underwent OLT from January 2001 to December 2005 were included in this study. The DeltaNa(+) for each donor recipient pair was correlated with standard postoperative liver function tests as well as recipient length of intensive care unit stay (LOICUS), length of hospital stay (LOHS) and recipient survival. The relationship between donor hypernatremia (serum sodium >or= 155 mEq/mL), recipient hyponatremia (serum sodium level |
| Databáze: | OpenAIRE |
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