Evaluation of Foveal Avascular Zone and Capillary Plexuses in Diabetic Patients by Optical Coherence Tomography Angiography
| Autor: | Emine Ciloglu, Fikret Unal, Yusuf Koçluk, Emine Alyamaç Sukgen |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Fovea Centralis medicine.medical_specialty Fundus Oculi Optic coherence tomography angiography Foveal avascular zone Age and sex chemistry.chemical_compound Ischemia Foveal Ophthalmology Healthy control medicine Humans Capillary plexus Prospective Studies Fluorescein Angiography Diabetic Retinopathy medicine.diagnostic_test business.industry Retinal Vessels General Medicine Diabetic retinopathy Optical coherence tomography angiography Middle Aged medicine.disease Capillaries Diabetes Mellitus Type 2 chemistry Case-Control Studies Angiography Disease Progression Female Original Article sense organs Glycated hemoglobin business Tomography Optical Coherence Follow-Up Studies |
| Zdroj: | Korean Journal of Ophthalmology : KJO |
| ISSN: | 2092-9382 1011-8942 |
| Popis: | Purpose To investigate the foveal avascular zone (AVZ), superficial and deep foveal and parafoveal vessel density (VD) changes related to diabetic retinopathy. Methods Forty-nine type 2 diabetes mellitus (DM) and 45 healthy control subjects were included in this study. The demographic data (age and sex), disease duration, and level of glycated hemoglobin were collected. Superficial VD (%), superficial AVZ area (mm2), deep VD (%) and deep AVZ area (mm2) were evaluated via optic coherence tomography angiography. Results Superficial AVZ was 0.438 ± 0.05 mm2 in the DM group, 0.246 ± 0.022 mm2 in the control group (p < 0.001). Deep AVZ was 0.732 ± 0.06 mm2 in the DM group, and 0.342 ± 0.022 mm2 in the control group (p < 0.001). Superficial foveal VD was 29.45 ± 0.76 mm2 in the DM group, and 34.86 ± 0.75 mm2 in the control group (p < 0.001). Deep foveal VD was 24.85 ± 1.08 mm2 in the DM group, and 33.47 ± 0.56 mm2 in the control group (p < 0.001). Conclusions In this study, we demonstrated an enlargement in the foveal AVZ along with a reduction in the vascular density of the superficial and deep capillary network in the foveal and parafoveal area using optic coherence tomography angiography in patients with nonproliferative diabetic retinopathy. This technique can be used to monitor the progression of the disease and to evaluate the response to treatment. |
| Databáze: | OpenAIRE |
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