A prospective study evaluating the impact of implementing the ERAS protocol on patients undergoing surgery for advanced ovarian cancer
| Autor: | Lipi Madhusudanan, Anupama Rajanbabu, Reshu Agarwal, P. V. Nitu, Unnikrishnan U G, Gaurav Goel |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Carcinoma Ovarian Epithelial 03 medical and health sciences Young Adult 0302 clinical medicine Postoperative Complications Laparotomy medicine Humans Prospective Studies Prospective cohort study Aged Protocol (science) Aged 80 and over Ovarian Neoplasms Advanced ovarian cancer Analgesics 030219 obstetrics & reproductive medicine business.industry Incidence (epidemiology) Obstetrics and Gynecology Cytoreduction Surgical Procedures Middle Aged Debulking Surgery Treatment Outcome Oncology 030220 oncology & carcinogenesis Cohort Antiemetics Fluid Therapy Female University teaching business |
| Zdroj: | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society. 29(3) |
| ISSN: | 1525-1438 |
| Popis: | ObjectiveInformation on the benefits of enhanced recovery after surgery (ERAS) when applied to advanced ovarian cancer() is minimal. The study objectives were to prospectively evaluate whether the implementation of ERAS in AOC patients improves post-operative recovery, and reduces the length of hospital stay (LOHS), without increasing the readmission rate or surgery-related complications; and to investigate ERAS protocol compliance.MethodsThis was a prospective interventional study carried out at a single university teaching hospital. Patients undergoing laparotomy for advanced ovarian cancer (stages IIb–IV) from March 2017 to February 2018 were managed using an ERAS protocol. The conventional management (CM) period extended from January 2016 to December 2016. The primary outcome was reduction in LOHS. Secondary outcomes were ERAS protocol compliance, incidence of post-operative complications, and readmission rate.ResultsThe CM and ERAS groups each comprised 45 patients. Both the groups were comparable in terms of clinicopathological and operative characteristic. Median LOHS of the full cohort, primary debulking cohort, interval debulking cohort, staging surgery cohort (all 6 vs 4 days; pConclusionThe results from our investigation suggest that the ERAS program can be successfully implemented in advanced ovarian cancer patients even in low-resource settings provided the program is modified to meet local needs so as not to increase healthcare costs. |
| Databáze: | OpenAIRE |
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