| Autor: |
Chen, Miaoqin, Wang, Weikai, Hu, Shiman, Tong, Yifan, Li, Yiling, Wei, Qi, Yu, Lei, Zhu, Liyuan, Zhu, Yiran, Liu, Leiming, Ju, Zhenyu, Wang, Xian, Jin, Hongchuan, Feng, Lifeng |
| Rok vydání: |
2022 |
| DOI: |
10.6084/m9.figshare.19445843 |
| Popis: |
Additional file 1. Additional results, figures, protocols and tables. Supplementary Figures S1-S6 show additional data related to the results shown in the main figures. Supplemental Figure 1. WIP1 inhibition suppresses HCC cell proliferation in vitro. Supplemental Figure 2. WIP1 inhibition suppresses HCC development in vivo. Supplemental Figure 3. WIP1 inhibition disrupts DNA damage repair by increasing H2AX phosphorylation. Supplemental Figure 4. WIP1 inhibition disrupts DNA damage repair by increasing H2AX phosphorylation. Supplemental Figure 5. WIP1 and PARP inhibition enhances DNA damage. Supplemental Figure 6. WIP1 and PARP inhibition induce synthetic lethality of HCC cells in vitro. Table S1. siRNA sequences used for knockdown. Table S2. shRNA sequences used for knockdown. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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