Addressing sexual dysfunction after risk-reducing salpingo-oophorectomy: Effects of a brief, psychosexual intervention
| Autor: | Andrea Farkas Patenaude, Jennifer Bakan, Judy Garber, Sharon L. Bober, Christopher J. Recklitis |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Adult
medicine.medical_specialty Urology Endocrinology Diabetes and Metabolism medicine.medical_treatment Ovariectomy Sexual Behavior Directive Counseling Pilot Projects Personal Satisfaction Body awareness Article law.invention Salpingectomy Endocrinology Randomized controlled trial Telephone counseling Quality of life law medicine Humans Genetic Predisposition to Disease Gynecology BRCA2 Protein Ovarian Neoplasms Cognitive Behavioral Therapy business.industry BRCA1 Protein medicine.disease Self Efficacy Cognitive behavioral therapy Psychiatry and Mental health Sexual dysfunction Reproductive Medicine Mutation Cognitive therapy Physical therapy Quality of Life Feasibility Studies Female medicine.symptom business Somatization Risk Reduction Behavior |
| Popis: | Introduction Women at high risk for ovarian cancer due to BRCA1 or BRCA 2 mutation or family history are recommended to undergo risk-reducing salpingo-oophorectomy (RRSO) after age 35 or completion of childbearing. This potentially life-saving surgery leads to premature menopause, frequently resulting in distressing and unaddressed sexual dysfunction. Aim To pilot a novel sexual health intervention for women with BRCA1/2 mutations who previously underwent RRSO a using a single-arm trial. Feasibility and primary outcomes including sexual dysfunction and psychological distress were assessed. Methods This single-arm trial included a one-time, half-day educational session comprised of targeted sexual health education, body awareness and relaxation training, and mindfulness-based cognitive therapy strategies, followed by two sessions of tailored telephone counseling. Assessments were completed at baseline and 2 months postintervention. Main Outcome Measure Study end points include feasibility and effectiveness as reported by the participant. Results Thirty-seven women completed baseline and postintervention assessments. At baseline, participants had a mean age of 44.4 (standard deviation [SD] = 3.9) years and mean duration of 3.8 (SD = 2.7) years since RRSO. Overall sexual functioning (P = 0.018), as well as desire (P = 0.003), arousal (P = 0.003), satisfaction (P = 0.028), and pain (P = 0.018), improved significantly. There were significant reductions in somatization (P = 0.029) and anxiety scores (P Conclusions This intervention integrates elements of cognitive behavioral therapy with sexual health education to address a much-neglected problem after RRSO. Results from this promising single-arm study provide preliminary data to move toward conducting a randomized, controlled trial. |
| Databáze: | OpenAIRE |
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