A sex-inducing pheromone triggers cell cycle arrest and mate attraction in the diatom Seminavis robusta
| Autor: | Per Winge, Julia Scharf, Sam De Decker, Johannes Frenkel, Christine Lembke, Marnik Vuylsteke, Jeroen Gillard, Koen Sabbe, Georg Pohnert, Tore Brembu, Valerie Devos, Atle M. Bones, Koen Van den Berge, Lieven Clement, Lieven De Veylder, Marie J. J. Huysman, Sara Moeys, Barbara Bouillon, Wim Vyverman |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0106 biological sciences
0301 basic medicine Mating type Proline Transcription Genetic Glutamic Acid Mitosis RECOMBINATION 01 natural sciences Article Transcriptome 03 medical and health sciences Sexual Behavior Animal GUANYLYL CYCLASES Botany Animals Metabolomics Sex Attractants Diatoms Multidisciplinary biology IDENTIFICATION Phosphoric Diester Hydrolases fungi MATING SYSTEM Biology and Life Sciences Cell Cycle Checkpoints biology.organism_classification Mating system MEIOSIS Attraction GENE Sexual reproduction Cell biology CD-HIT GENOME Meiosis REPRODUCTION 030104 developmental biology Diatom Gene Expression Regulation Guanylate Cyclase DIFFERENTIAL EXPRESSION ANALYSIS Metabolome Pheromone Metabolic Networks and Pathways 010606 plant biology & botany |
| Zdroj: | SCIENTIFIC REPORTS Scientific Reports |
| ISSN: | 2045-2322 |
| Popis: | Although sexual reproduction is believed to play a major role in the high diversification rates and species richness of diatoms, a mechanistic understanding of diatom life cycle control is virtually lacking. Diatom sexual signalling is controlled by a complex, yet largely unknown, pheromone system. Here, a sex-inducing pheromone (SIP+) of the benthic pennate diatom Seminavis robusta was identified by comparative metabolomics, subsequently purified and physicochemically characterized. Transcriptome analysis revealed that SIP+ triggers the switch from mitosis-to-meiosis in the opposing mating type, coupled with the transcriptional induction of proline biosynthesis genes and the release of the proline-derived attraction pheromone. The induction of cell cycle arrest by a pheromone, chemically distinct from the one used to attract the opposite mating type, highlights the existence of a sophisticated mechanism to increase chances of mate finding, while keeping the metabolic losses associated with the release of an attraction pheromone to a minimum. |
| Databáze: | OpenAIRE |
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