Occurrence of Acrylamide in Italian Baked Products and Dietary Exposure Assessment

Autor: Salvatore Velotto, Tommaso Stasi, Teresa Rea, Francesco Esposito, Teresa Cirillo
Přispěvatelé: Esposito, F., Velotto, S., Rea, T., Stasi, T., Cirillo, T.
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Carcinogenesis
Pharmaceutical Science
Food Contamination
Biology
01 natural sciences
Article
Gas Chromatography-Mass Spectrometry
Analytical Chemistry
Dietary Exposure
lcsh:QD241-441
chemistry.chemical_compound
0404 agricultural biotechnology
lcsh:Organic chemistry
Age groups
Drug Discovery
otorhinolaryngologic diseases
Cooking
Food science
Physical and Theoretical Chemistry
Risk assessment
Acrylamide
Dietary exposure
Bromination
010401 analytical chemistry
Organic Chemistry
digestive
oral
and skin physiology

Temperature
technology
industry
and agriculture

food and beverages
Bread
04 agricultural and veterinary sciences
Bromine
040401 food science
Italian population
Margin of exposure
0104 chemical sciences
Italy
chemistry
Chemistry (miscellaneous)
Carcinogens
Molecular Medicine
2-propenamide
Food Analysis
2-Propenamide
Exposure data
Zdroj: Molecules
Volume 25
Issue 18
Molecules, Vol 25, Iss 4156, p 4156 (2020)
Popis: Acrylamide (AA) is a neo-formed toxic compound that develops in foods during cooking at temperatures above 120 °
C. AA shows in vivo neurotoxic and carcinogenic effects, and it is potentially carcinogenic for humans. Its occurrence is common in baked food, such as bread and similar products. This study set out to analyze bread and sweets from the Italian market to evaluate the effects of the benchmark thresholds set by EU Regulation 2017/2158 and to ascertain the exposure of the Italian population to AA, across three age groups, through the consumption of baked products, according to the margin of exposure (MOE) approach. Two hundred samples were tested, and the content of AA ranged from 31 to 454 µ
g/kg for bread and products thereof and from 204 to 400 µ
g/kg for the sweets category. The exposure data did not show any neurotoxic health concern, whereas the MOE related to the carcinogenic endpoint is well below the minimum safety value of 10,000.
Databáze: OpenAIRE