The role of bile acids in phalloidin poisoning
| Autor: | Ernst Petzinger, Max Frimmer, U. Rufeger, L. B. Veil |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Pharmacology
Time Factors Phalloidin Phalloidine Pharmacology toxicology macromolecular substances General Medicine In Vitro Techniques Rats Bile Acids and Salts Concentration dependent chemistry.chemical_compound chemistry Biochemistry Liver Block (telecommunications) Liver tissue polycyclic compounds Animals sense organs Oligopeptides |
| Zdroj: | Naunyn-Schmiedeberg's archives of pharmacology. 301(2) |
| ISSN: | 0028-1298 |
| Popis: | Glycocholate and other bile acids inhibit the response of isolated hepatocytes to phalloidin in a concentration dependent manner. It is suggested that the inhibition is due to a block of phalloidin uptake. This interaction might explain the high specificity of phalloidin for liver tissue. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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