Clostridioides difficile–Associated Diarrhea: Infection Prevention Unknowns and Evolving Risk Reduction Strategies

Autor:	Michael P. Stevens, Gonzalo Bearman, Michelle Doll, Michele Fleming
Rok vydání:	2019
Předmět:	medicine.medical_specialty Isolation (health care) business.industry Disease Diarrhea Infectious Diseases Epidemiology Health care medicine Antimicrobial stewardship Infection control medicine.symptom business Intensive care medicine Clostridioides
Zdroj:	Current Infectious Disease Reports. 21
ISSN:	1534-3146 1523-3847
DOI:	10.1007/s11908-019-0659-8
Popis:	New controversies in the diagnosis and prevention of Clostridiodes difficile are challenging and at times changing infection control practice at many medical centers. Molecular epidemiologic studies are changing our understanding of C. difficile and its spectrum of disease. C. difficile as a hospital-acquired infection is likely largely overdiagnosed given overly sensitive molecular testing and widespread colonization of ill or debilitated patients. Clostridiodes difficile infection continues to challenge infection prevention programs. Shifts in our understanding of the epidemiology of this organism and its spectrum of clinical presentations are changing the approach to prevention efforts. Nevertheless, cleanliness of the healthcare environment and antimicrobial stewardship remain core risk reduction strategies. Other strategies such as screening and isolation are inciting controversy. The optimal infection prevention strategies for C. difficile remain the subject of intense study and debate.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0808974c9d6a4ef648193431549e9cdb https://doi.org/10.1007/s11908-019-0659-8 Zobrazit plný text záznamu Full text from SpringerLink