Corrigendum to ’Endometrial membrane organoids from human embryonic stem cell combined with the 3D Matrigel for endometrium regeneration in asherman syndrome’ [Bioactive Mater. 6 (2021) 3935–3946]
| Autor: | Xingmiao Li, Meijun Guo, Yangyang Li, Xiangwei Fei, Jiajie Shen, Jianhua Chen, Xiuxiu Jiang |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Matrigel
QH301-705.5 business.industry Regeneration (biology) Biomedical Engineering Endometrium Embryonic stem cell Article Cell biology Biomaterials medicine.anatomical_structure Asherman Syndrome TA401-492 medicine Organoid Biology (General) business Materials of engineering and construction. Mechanics of materials Biotechnology |
| Zdroj: | Bioact Mater Bioactive Materials, Vol 6, Iss 12, Pp 4591-(2021) |
| Popis: | Asherman's syndrome (AS), a leading cause of uterine infertility worldwide, is characterized by scarring of the uterine surfaces lacking endometrial epithelial cells, which prevents endometrial regeneration. Current research on cell therapy for AS focuses on mesenchymal and adult stem cells from the endometrium. However, insufficient number, lack of purity, and rapid senescence of endometrial epithelial progenitor cells (EEPCs) during experimental processes restrict their use in cell therapies. In this study, we induced human embryonic stem cells-9 (H9-ESC) into EEPCs by optimizing the induction factors from the definitive endoderm. EEPCs, which act as endometrial epithelial cells, accompanied by human endometrial stromal cells provide a niche environment for the development of endometrial membrane organoids (EMOs) in an |
| Databáze: | OpenAIRE |
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