Pyridoxic acid excretion during low vitamin B-6 intake, total fasting, and bed rest
| Autor: | H W Lane, J D Mahuren, P S Conn, D. R. Pearson, K G Thampy, D L Costill, W J Fink, Stephen P. Coburn, W E Schaltenbrand, P J Ziegler |
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| Rok vydání: | 1995 |
| Předmět: |
Adult
Male Vitamin medicine.medical_specialty Pyridoxic Acid Normal diet medicine.medical_treatment Medicine (miscellaneous) Biology Bed rest Excretion chemistry.chemical_compound Internal medicine medicine Humans Muscle Skeletal Nutrition and Dietetics Pyridoxine Fasting Metabolism Diet B vitamins Endocrinology chemistry Pyridoxal Phosphate Female Vitamin B 6 Deficiency Bed Rest medicine.drug |
| Zdroj: | The American Journal of Clinical Nutrition. 62:979-983 |
| ISSN: | 0002-9165 |
| Popis: | Vitamin B-6 metabolism in 10 volunteers during 21 d of total fasting was compared with results from 10 men consuming a diet low only in vitamin B-6 (1.76 mumol/d) and with men consuming a normal diet during bed rest. At the end of the fast mean plasma concentrations of vitamin B-6 metabolites and urinary excretion of 4-pyridoxic acid tended to be higher in the fasting subjects than in the low-vitamin B-6 group. The fasting subjects lost approximately 10% of their total vitamin B-6 pool and approximately 13% of their body weight. The low-vitamin B-6 group lost only approximately 4% of their vitamin B-6 pool. Compared with baseline, urinary excretion of pyridoxic acid was significantly increased during 17 wk of bed rest. There was no increase in pyridoxic acid excretion during a second 15-d bed rest study. These data suggest the possibility of complex interactions between diet and muscle metabolism that may influence indexes that are frequently used to assess vitamin B-6 status. |
| Databáze: | OpenAIRE |
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