| Autor: |
Robert J. Gillies, Robert A. Gatenby, Joseph Johnson, Bonnie F. Sloane, Jennifer M. Rothberg, Yoganand Balagurunathan, Kate Bailey, Arig Ibrahim-Hashim, Heather H. Cornnell, Jonathan Wojtkowiak, Mark Lloyd, Tingan Chen, Veronica Estrella |
| Rok vydání: |
2023 |
| DOI: |
10.1158/0008-5472.22399056 |
| Popis: |
PDF file - 50K, Figure S6: Ex vivo comparison of vessel density in stroma vs tumor tissue. Using the Image Scope v7.1 regions of viable tumor were manually selected. 200�m micrometers were placed around the circumference of the tumor region perpendicular to the tumor edge. A second manually selected region was drawn around the perimeter of the micrometers. This effectively segments the entire tissue section into three regions of interest; the tumor, the edge within 200�m of the tumor and the distant stromal region. The Aperio (Vista, CA, USA) microvessel algorithm v1.0 was used with the following parameters (smoothing 2; dark threshold160; light threshold 210; regioning 6; completion 7) to identify the vascular density which was defined as the vessel area divided by total area (�m2). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
