Synthesis and antifungal activities of natural and synthetic biflavonoids
| Autor: | Gabriel Sagrera, Ana Bertucci, Alvaro Vázquez, Gustavo Seoane |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Antifungal
Ullmann condensation Antifungal Agents medicine.drug_class Clinical Biochemistry Pharmaceutical Science Microbial Sensitivity Tests Biochemistry Chemical synthesis High yielding chemistry.chemical_compound Aldol reaction Drug Discovery medicine Biflavonoids Humans Organic chemistry Molecular Biology Molecular Structure Flavone derivatives Organic Chemistry Fungi Monomer Mycoses chemistry Molecular Medicine |
| Zdroj: | Bioorganic & Medicinal Chemistry. 19:3060-3073 |
| ISSN: | 0968-0896 |
| DOI: | 10.1016/j.bmc.2011.04.010 |
| Popis: | The synthesis of some natural and synthetic biflavonoids was performed in good overall yields starting from readily available materials via high yielding aldol and Ullmann condensations. Some of these compounds, especially bichalcones, display an interesting activity against fungi, higher than that of the corresponding monomers. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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