Primary lateral sclerosis-like picture in a patient with a remote history of anti-N-methyl-D- aspartate receptor (anti-NMDAR) antibody encephalitis
| Autor: | Merrilee Needham, Mubeen Janmohamed, Sam Salman, Wally Knezevic |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Adult Pathology medicine.medical_specialty Ataxia Neurology Receptors N-Methyl-D-Aspartate 03 medical and health sciences 0302 clinical medicine Recurrence Positron Emission Tomography Computed Tomography medicine Humans Motor Neuron Disease Gait Disorders Neurologic Primary Lateral Sclerosis Autoantibodies Diplopia Anti-N-Methyl-D-Aspartate Receptor Encephalitis business.industry Brain General Medicine medicine.disease Magnetic Resonance Imaging 030104 developmental biology Upper motor neuron syndrome Muscle Spasticity NMDA receptor Female medicine.symptom business Motor neurone disease 030217 neurology & neurosurgery Encephalitis Findings That Shed New Light on the Possible Pathogenesis of a Disease or an Adverse Effect |
| Zdroj: | BMJ Case Rep |
| ISSN: | 1757-790X |
| Popis: | Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a well-recognised disorder, first fully characterised in 2007. The long-term sequelae reported thus far include relapses with typical, as well as partial aspects of the well-defined neuropsychiatric syndrome. Rarely, isolated atypical symptoms (diplopia, ataxia and tremor) have been reported as relapse phenomenon. We report a case of a patient with a remote history of likely anti-NMDAR encephalitis with the longest follow-up reported in the literature to date (22 years). The relapse presentation was of a purely upper motor neuron syndrome with a primary lateral sclerosis-like picture. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|