There is an individual tolerance to mechanical loading in compression induced deep tissue injury
| Autor: | Willeke A. Traa, Mark C. van Turnhout, Jules L. Nelissen, Cees W. J. Oomens, Gustav J. Strijkers, Dan L. Bader |
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| Přispěvatelé: | ACS - Atherosclerosis & ischemic syndromes, ANS - Brain Imaging, Biomedical Engineering and Physics, AMS - Sports & Work, ACS - Heart failure & arrhythmias, Soft Tissue Biomech. & Tissue Eng. |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Materials science
3d analysis Biophysics Deep tissue injury Individual susceptibility Rats Sprague-Dawley 03 medical and health sciences Imaging Three-Dimensional 0302 clinical medicine Tibialis anterior muscle Deep tissue Indentation Mechanical compression Pressure Animals Orthopedics and Sports Medicine Muscle Skeletal Pressure ulcers Pressure Ulcer Subject specific Finite element analysis 030229 sport sciences Compression (physics) Magnetic Resonance Imaging Rats Female Stress Mechanical Algorithms 030217 neurology & neurosurgery Biomedical engineering MRI |
| Zdroj: | Clinical biomechanics (Bristol, Avon), 63, 153-160. Elsevier Limited Clinical Biomechanics, 63, 153-160. Elsevier |
| ISSN: | 0268-0033 |
| Popis: | Background: deep tissue injury is a type of pressure ulcer which originates subcutaneously due to sustained mechanical loading. The relationship between mechanical compression and damage development has been extensively studied in 2D. However, recent studies have suggested that damage develops beyond the site of indentation. The objective of this study was to compare mechanical loading conditions to the associated damage in 3D. Methods: an indentation test was performed on the tibialis anterior muscle of rats (n = 39). Changes in the form of oedema and structural damage were monitored with MRI in an extensive region. The internal deformations were evaluated using MRI based 3D finite element models. Findings: damage propagates away from the loaded region. The 3D analysis indicates that there is a subject specific tolerance to compression induced deep tissue injury. Interpretation: Individual tolerance is an important factor when considering the mechanical loading conditions which induce damage. |
| Databáze: | OpenAIRE |
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