| Autor: |
Wei Ba, Huan Wu, Wei W. Chen, Shu H. Wang, Zi Y. Zhang, Xuan J. Wei, Wen J. Wang, Lei Yang, Dong M. Zhou, Yi X. Zhuang, Qin Zhong, Zhi G. Song, Cheng X. Li |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
European journal of cancer (Oxford, England : 1990). 169 |
| ISSN: |
1879-0852 |
| Popis: |
Convolutional neural networks (CNNs) have demonstrated expert-level performance in cutaneous tumour classification using clinical images, but most previous studies have focused on dermatologist-versus-CNN comparisons rather than their combination. The objective of our study was to evaluate the potential impact of CNN assistance on dermatologists for clinical image interpretation.A multi-class CNN was trained and validated using a dataset of 25,773 clinical images comprising 10 categories of cutaneous tumours. The CNN's performance was tested on an independent dataset of 2107 images. A total of 400 images (40 per category) were randomly selected from the test dataset. A fully crossed, self-control, multi-reader multi-case (MRMC) study was conducted to compare the performance of 18 board-certified dermatologists (experience: 13/18 ≤ 10 years; 5/18＞10 years) in interpreting the 400 clinical images with or without CNN assistance.The CNN achieved an overall accuracy of 78.45% and kappa of 0.73 in the classification of 10 types of cutaneous tumours on 2107 images. CNN-assisted dermatologists achieved a higher accuracy (76.60% vs. 62.78%, P 0.001) and kappa (0.74 vs. 0.59, P 0.001) than unassisted dermatologists in interpreting the 400 clinical images. Dermatologists with less experience benefited more from CNN assistance. At the binary classification level (malignant or benign), the sensitivity (89.56% vs. 83.21%, P 0.001) and specificity (87.90% vs. 80.92%, P 0.001) of dermatologists with CNN assistance were also significantly improved than those without.CNN assistance improved dermatologist accuracy in interpreting cutaneous tumours and could further boost the acceptance of this new technique. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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