Pharmacological actions of tannic acid; II. Evaluation of CNS activity in animals
| Autor: | Reinaldo N. Takahashi, T. C. M. De Lima, Gina Struffaldi Morato |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Male
medicine.drug_class Pharmaceutical Science Pharmacology Motor Activity Median lethal dose Analytical Chemistry Lethal Dose 50 chemistry.chemical_compound Mice Inbred strain Drug Discovery Tannic acid medicine Tannin Animals Cns activity chemistry.chemical_classification Behavior Animal Organic Chemistry Convulsive threshold Biological activity Rats Inbred Strains Hydrolyzable Tannins Rats Complementary and alternative medicine Biochemistry chemistry Molecular Medicine Depressant Tannins |
| Zdroj: | Planta medica. (4) |
| ISSN: | 0032-0943 |
| Popis: | The effects of tannic acid (TA) on some behavioral tests in animals were investigated. A non-specific depressant action of TA was the most salient finding in the present study since TA reduced locomotor activity, potentiated pentobarbital-induced sleeping-time and induced analgesia in mice. No changes were found on the convulsive threshold test in rats. It is concluded that the reported central depressant effects of some crude extracts from plant material could be due to the presence of tannin-like constituents in the plant. |
| Databáze: | OpenAIRE |
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