Rates of Formation and Absorption of Cerebrospinal Fluid in Bovine Hypovitaminosis A

Autor: H.D. Hurt, H.D. Eaton, R.C. Hall, M.C. Calhoun, J.E. Rousseau
Rok vydání: 1967
Předmět:
Zdroj: Journal of Dairy Science. 50:1486-1494
ISSN: 0022-0302
DOI: 10.3168/jds.s0022-0302(67)87653-7
Popis: Ventriculocisternal perfusion (VCP) was used to determine the rates of bulk absorption (inulin clearance, C In ) and formation ( V ˙ f ) of cerebrospinal fluid (CSF) in nine hypovitaminotic A and ten vitamin A adequate calves. The average intraventricular CSF pressures were 374 and 54mm of synthetic CSF for the deficient and adequate calves, respectively, with corresponding plasma vitamin A concentrations of 5 and 29μg/100ml. Regressions of C In and V ˙ f , both in g/min, on perfusion pressure (−100, 0, or +200mm of synthetic CSF relative to the initially determined CSF pressure), X, were, respectively, for the deficient and adequate calves : C In = 0.258 + 0.00062 X and C In = 0.318 + 0.00111 X (SD = 0.038) ; V ˙ f = 0.312 − 0.00016 X and V ˙ f = 0.328 − 0.00030 X \( SD = 0.034 \) . The magnitude of the response to the induced VCP pressures was significantly less for C In in the deficient calves; whereas, for V f , differences were not significant. Thus, absorption of CSF is impaired in hypovitaminotic A calves.
Databáze: OpenAIRE