Prospective Clinical Applications of CRF Peptide Antagonists
| Autor: | Jean Rivier |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
endocrine system
Corticotropin-Releasing Hormone Peptide Anxiety 030204 cardiovascular system & hematology Bioinformatics Irritable Bowel Syndrome 03 medical and health sciences 0302 clinical medicine Astressin-B Stress Physiological Neoplasms Drug Discovery 0502 economics and business Animals Humans Medicine Amino Acid Sequence chemistry.chemical_classification business.industry 05 social sciences General Medicine chemistry 050211 marketing Peptides business hormones hormone substitutes and hormone antagonists |
| Zdroj: | Current Molecular Pharmacology. 10 |
| ISSN: | 1874-4672 |
| DOI: | 10.2174/1874467210666170110112914 |
| Popis: | It is noteworthy that thirty three years of efforts in corticotropin releasing factor (CRF) research by academia and the pharmaceutical industry resulted in several thousand papers and patents, yet little progress has been made to identify and market diagnostic or therapeutic CRF peptides and small molecule ligands. We document the potential relevance of CRF peptide antagonists to reinvigorate stress/anxiety affected "anatomy systems" in order to boost their efficacy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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