A case-control study of risk factors for death from 2009 pandemic influenza A(H1N1): is American Indian racial status an independent risk factor?
Autor: | Hennessy, T. W., Bruden, D., Castrodale, L., Komatsu, K., Erhart, L. M., Thompson, David, Bradley, K., O'Leary, D. R., McLaughlin, J., Landen, M., Bentley, Steve, Keck, James, Kitka, Sassa, Thompson, Gail, Fearey, Donna, Redwood, Diana, Craig, Jessica, Provost, Ellen, Robinson, Keisha, Noble, Rhonda, Burnsed, Laurence, Dougherty, Kendra, Lee, Anthony, McDonald-Hamm, Christie, Smithee, Laura, Williams, Jean, McClinton, Reginald, Tran, Annie, Redd, John, Cheek, James, Bryan, Ralph, Jhung, Michael, Tarkhashvili, Nato, Danila, Richard, Leman, Richard, Wells, Eden, Lofy, Kathy, Miller, Tracy |
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Rok vydání: | 2015 |
Předmět: |
Adult
Pediatrics medicine.medical_specialty Adolescent Epidemiology Article Young Adult 03 medical and health sciences Influenza A Virus H1N1 Subtype 0302 clinical medicine Risk Factors Influenza Human Pandemic Health care Humans Medicine 030212 general & internal medicine Risk factor Young adult Child Pandemics Aged 030505 public health business.industry pandemic Medical record Infant Newborn Pandemic influenza Case-control study Infant Middle Aged United States Infectious Diseases Immunization Case-Control Studies Child Preschool Indians North American influenza 0305 other medical science business Infectious disease epidemiology Demography |
Zdroj: | Epidemiology and Infection. 144:315-324 |
ISSN: | 1469-4409 0950-2688 |
DOI: | 10.1017/s0950268815001211 |
Popis: | SUMMARYHistorically, American Indian/Alaska Native (AI/AN) populations have suffered excess morbidity and mortality from influenza. We investigated the risk factors for death from 2009 pandemic influenza A(H1N1) in persons residing in five states with substantial AI/AN populations. We conducted a case-control investigation using pandemic influenza fatalities from 2009 in Alaska, Arizona, New Mexico, Oklahoma and Wyoming. Controls were outpatients with influenza. We reviewed medical records and interviewed case proxies and controls. We used multiple imputation to predict missing data and multivariable conditional logistic regression to determine risk factors. We included 145 fatal cases and 236 controls; 22% of cases were AI/AN. Risk factors (P < 0·05) included: older age [adjusted matched odds ratio (mOR) 3·2, for >45 years vs. |
Databáze: | OpenAIRE |
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