Functionalization of Elongated Tetrahexahedral Au Nanoparticles and Their Antimicrobial Activity Assay
| Autor: | Suresh K. Bhargava, Arpita Poddar, Ravi Shukla, Ahmad Esmaielzadeh Kandjani, Ylias M. Sabri, Chaitali Dekiwadia, Shakil Ahmed Polash, Satya Ranjan Sarker, Jarryd M. Boath |
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| Rok vydání: | 2019 |
| Předmět: |
Materials science
Metal Nanoparticles Nanoparticle Antineoplastic Agents 02 engineering and technology Antioxidants Lipid peroxidation 03 medical and health sciences chemistry.chemical_compound Anti-Infective Agents Escherichia coli Humans General Materials Science Cell Proliferation 030304 developmental biology 0303 health sciences Thioctic Acid 021001 nanoscience & nanotechnology Antimicrobial Combinatorial chemistry Lipoic acid chemistry Colloidal gold Surface modification Biological Assay Gold 0210 nano-technology Antibacterial activity Bacillus subtilis HeLa Cells |
| Zdroj: | ACS Applied Materials & Interfaces. 11:13450-13459 |
| ISSN: | 1944-8252 1944-8244 |
| Popis: | Gold nanoparticles are inert for the human body, and therefore, they have been functionalized to provide them with antibacterial properties. Here, elongated tetrahexahedral (ETHH) Au nanoparticles were synthesized, characterized, and functionalized with lipoic acid (LA), a natural antioxidant with a terminal carboxylic acid and a dithiolane ring, to generate ETHH-LA Au nanoparticles. The antioxidant activity of Au nanoparticles was investigated in vitro, showing that LA enhances the 2,2-diphenyl-1-picrylhydrazyl free-radical scavenging and Fe |
| Databáze: | OpenAIRE |
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