Motorized fractional flow reserve pullback

Autor: Takuya Mizukami, Jean F. Argacha, Daniele Andreini, Emanuele Barbato, Jeroen Sonck, Antonio L. Bartorelli, B Vandeloo, Carlos Collet, Bernard De Bruyne, Bernard Cosyns
Přispěvatelé: Clinical sciences, Cardiology, Cardio-vascular diseases, Graduate School, ACS - Heart failure & arrhythmias, Sonck, J., Collet, C., Mizukami, T., Vandeloo, B., Argacha, J. F., Barbato, E., Andreini, D., Bartorelli, A., Cosyns, B., De Bruyne, B.
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Male
Cardiac Catheterization
medicine.medical_specialty
Myocardial revascularization
Clinical Decision-Making
Coronary Artery Disease
Fractional flow reserve
030204 cardiovascular system & hematology
Coronary Angiography
Severity of Illness Index
Coronary artery disease
03 medical and health sciences
Percutaneous Coronary Intervention
0302 clinical medicine
Pullback
Predictive Value of Tests
Internal medicine
FRACTIONAL FLOW RESERVE
medicine
Humans
Radiology
Nuclear Medicine and imaging
In patient
030212 general & internal medicine
Aged
Reproducibility
business.industry
Coronary Stenosis
Reproducibility of Results
General Medicine
Repeatability
Middle Aged
medicine.disease
Fractional Flow Reserve
Myocardial
Anatomical landmark
myocardial revascularization
Cardiology
Female
Stable coronary artery disease
motorized FFR pullbacks
business
Cardiology and Cardiovascular Medicine
Zdroj: Catheterization and cardiovascular interventions, 96(3), E230-E237. Wiley-Liss Inc.
ISSN: 1522-1946
Popis: Objectives The present study aimed at determining the accuracy and reproducibility of motorized FFR pullbacks in patients with stable coronary artery disease. Background Fractional flow reserve (FFR) is recommended for decision making regarding myocardial revascularization. The distribution of epicardial resistance along coronary vessels can be assessed using FFR pullbacks. Methods Duplicated FFR pullbacks were acquired using a motorized device at a speed of 1 mm/s in intermediate coronary stenosis. In addition, a single FFR value was measured at an anatomical landmark. The agreement between FFR measurements was assessed using the Bland-Altman method, Pearson's correlation coefficient and area under the pullback curve (AUPC). Results In 20 vessels, 37,326 FFR values were obtained. The mean FFR from the pullbacks was 0.91 ± 0.08 whereas the mean FFR at the distal location was 0.85 ± 0.09. The mean difference between pullbacks was -0.002 (LOA -0.058 to 0.054). The difference in AUPC between the two FFR pullbacks was 2.1 ± 1.6%. At pre-specified anatomical locations, the mean difference between the FFR derived from the pullback data and the measured FFR was 0 (LOA -0.040 to 0.039). The repeatability of the distal FFR measurement was high (bias -0.003, LOA -0.046 to 0.041). Conclusion A motorized FFR pullback was accurate to assess the distribution of epicardial resistance in patients with intermediate coronary artery disease. The reproducibility of the FFR pullback was high. Further studies are required to determine the potential usefulness of a hyperemic FFR pullback strategy for decision making and treatment planning.
Databáze: OpenAIRE
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