Visit-to-visit variability in systolic blood pressure: correlated with the changes of arterial stiffness and myocardial perfusion in on-treated hypertensive patients
Autor: | Zhendong Liu, Jianchao Xu, Lin Ye, Fang Wei, Yutao Diao, Hongbin Song, Zaiwen Qi, Hua Zhang, Fanghong Lu, Yingxin Zhao |
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Rok vydání: | 2014 |
Předmět: |
Male
medicine.medical_specialty Physiology Coefficient of variation Blood Pressure Pulse Wave Analysis Vascular Stiffness Heart Rate Internal medicine Heart rate Internal Medicine medicine Humans Pulse wave velocity Antihypertensive Agents Aged business.industry Blood Pressure Determination General Medicine Middle Aged Aortic Augmentation Index medicine.disease Carotid Arteries Blood pressure medicine.anatomical_structure Hypertension Arterial stiffness Cardiology Female business Perfusion Blood Flow Velocity Artery |
Zdroj: | Clinical and Experimental Hypertension. 37:63-69 |
ISSN: | 1525-6006 1064-1963 |
DOI: | 10.3109/10641963.2014.897724 |
Popis: | Visit-to-visit variability in blood pressure (BP) was demonstrated to correlate with cardiovascular events independent of mean BP. The goal of the present study was to investigate the correlation of visit-to-visit BP variability with artery stiffness and myocardial perfusion in on-treated hypertensive patients.BP was measured in 271 hypertensive patients at every visit over the course of the antihypertensive treatment, and the standard deviation (SD), coefficient of variation (CV), maximum, and minimum in serial BP were calculated. Non-invasive pulse wave analysis was performed in all patients.Compared with baseline, carotid-femoral pulse wave velocity (cfPWV), aortic augmentation index (Aix) and Aix adjusted to a "standard heart rate" of 75 beats/min (Aix@HR75) were markedly declined, and sub-endocardial viability ratio (SEVR) was obviously increased in each group (p 0.001). The changes of cfPWV, SEVR, Aix and Aix@HR75 in patients with lower SD of systolic blood pressure (SBP) were significantly greater than those in patients with higher SD of SBP. And the changes were statistically correlated with both SD and CV of serial SBP during follow-up, even after adjusted for mean SBP and mean diastolic blood pressure (DBP).Visit-to-visit SBP variability is independently correlated with changes of artery stiffness and myocardial perfusion in on-treated hypertensive patients. |
Databáze: | OpenAIRE |
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