Downstream of homeotic genes: in the heart of Hox function
| Autor: | Monier, Bruno, Tevy, Maria Florencia, Perrin, Laurent, Capovilla, Maria, Tevy, Florencia, Sémériva, Michel |
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| Přispěvatelé: | Institut de Biologie du Développement de Marseille (IBDM), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Dulbecco Telethon Institute, Telethon Foundation |
| Rok vydání: | 2008 |
| Předmět: |
Cell type
[SDV]Life Sciences [q-bio] Organogenesis Computational biology [SDV.BC]Life Sciences [q-bio]/Cellular Biology Biology 03 medical and health sciences 0302 clinical medicine Homeotic selector gene Animals Drosophila Proteins Hox gene ComputingMilieux_MISCELLANEOUS 030304 developmental biology 0303 health sciences Genes Homeobox [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biology [SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal genetics [SDV.BDD.EO]Life Sciences [q-bio]/Development Biology/Embryology and Organogenesis Drosophila melanogaster Gene Expression Regulation Insect Science Identification (biology) Homeotic gene 030217 neurology & neurosurgery Function (biology) |
| Zdroj: | Fly Fly, Taylor & Francis, 2014, 1 (2), pp.59-67. ⟨10.4161/fly.3993⟩ Fly, Taylor & Francis, 2007, 1, pp.59-67 Fly, 2007, 1 (2), pp.59--67. ⟨10.4161/fly.3993⟩ Fly, 2014, 1 (2), pp.59-67. ⟨10.4161/fly.3993⟩ Fly, 2007, 1, pp.59-67 |
| ISSN: | 1933-6934 1933-6942 |
| DOI: | 10.4161/fly.3993⟩ |
| Popis: | International audience; A functional organ is constituted of diverse cell types. Each one occupies a distinct position and is associated to specific morphological and physiological functions. The identification of the genetic programs controlling these elaborated and highly precise features of organogenesis is crucial to understand how a mature organ works under normal conditions, and how pathologies can develop. Recently, a number of studies have reported a critical role for Hox genes in one example of organogenesis: cardiogenesis in Drosophila. Beyond the interest in understanding the molecular basis of functional cardiogenesis, this system might provide a model for proposing new paradigms of how Hox genes achieve their action throughout development. |
| Databáze: | OpenAIRE |
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