A real-life analysis on the indications and prognostic relevance of perioperative chemotherapy in locally advanced resectable gastric adenocarcinoma
| Autor: | F, Pardo, J, Osorio, C, Miranda, S, Castro, M, Miró, A, Luna, E, Garsot, D, Momblán, G, Galofré, J, Rodríguez-Santiago, M, Pera, Carme, Balagué |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
0301 basic medicine Oncology Cancer Research medicine.medical_specialty Databases Factual Population Locally advanced Adenocarcinoma 03 medical and health sciences 0302 clinical medicine Stomach Neoplasms Internal medicine Perioperative chemotherapy medicine Humans Stage (cooking) education Aged Retrospective Studies education.field_of_study Proportional hazards model business.industry Standard treatment Age Factors Cancer General Medicine Middle Aged Prognosis medicine.disease Survival Analysis Treatment Outcome 030104 developmental biology Lymphatic Metastasis 030220 oncology & carcinogenesis Lymph Node Excision Female business Cohort study |
| Zdroj: | Clinical and Translational Oncology. 22:1335-1344 |
| ISSN: | 1699-3055 1699-048X |
| DOI: | 10.1007/s12094-019-02261-1 |
| Popis: | Perioperative chemotherapy (periCTX) based on the “MAGIC” scheme has become a standard treatment in Europe for locally advanced oesophagogastric cancer. We assessed implementation and long-term oncological outcomes of MAGIC periCTX for locally advanced gastric cancer. Population-based cohort study of all patients with locally advanced gastric cancer undergoing surgical resection with curative intent in Catalonia and Navarra (the first two autonomous communities included in the EURECCA Upper GI Spanish Working Group) between January 2011 and December 2013. The main variable was the percentage of patients treated with MAGIC periCTX. Kaplan–Meier analysis and Cox proportional hazards model were used to assess the survival benefit of periCTX. Among 814 patients, 217 (26.6%) received periCTX (especially patients more likely to receive it: aged |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink