Comparison of photodynamic therapy and navigated microsecond laser for chronic central serous chorioretinopathy
| Autor: | Bindu Rajesh, Jay Chhablani, Gachago Muchai Muriithi, Abhilash Goud, Cyprian Gabriel Ntomoka |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Visual acuity genetic structures medicine.medical_treatment Visual Acuity Photodynamic therapy Chronic central serous chorioretinopathy Article 03 medical and health sciences 0302 clinical medicine Primary outcome Ophthalmology Medicine Humans Macula Lutea Retrospective Studies Laser Coagulation Photosensitizing Agents business.industry Significant difference Retrospective cohort study Middle Aged eye diseases Retinal structure Central Serous Chorioretinopathy Photochemotherapy 030221 ophthalmology & optometry Female sense organs Subretinal fluid medicine.symptom business 030217 neurology & neurosurgery Tomography Optical Coherence |
| Popis: | OBJECTIVES: To compare the visual and anatomical outcomes after photodynamic therapy (PDT) and navigated microsecond laser (nMSL) for chronic central serous chorioretinopathy (CSCR). METHODS: This retrospective study included eyes with chronic CSCR who underwent either PDT or nMSL with a minimum of 6 months’ follow-up. Eyes with a history of treatment with any other modalities in the past or during 6 months post PDT or microsecond laser follow-up were excluded. Primary outcome measures included change in best-corrected visual acuity (BCVA) and central macular thickness (CMT). Secondary outcome measures included changes in subretinal fluid, hyper-reflective foci, cystic spaces, subfoveal choroidal thickness, and outer retinal structure integrity. RESULTS: Forty-five eyes of 39 subjects (PDT group—23 eyes, nMSL group—22 eyes) with chronic CSCR were analyzed. At 6 months’ follow-up, the nMSL group had significantly higher improvement in visual acuity compared to the PDT group (0.12 ± 0.24 vs −0.02 ± 0.20 (p = 0.039)). Reduction in central macular thickness was significantly higher in nMSL group compared to the PDT (85.5 ± 93.26 vs 24.47 ± 73.18 microns (p = 0.02)). Thirteen (59%) eyes in nMSL group had complete resolution of the SRF at 6 months compared to 5 (21.7%) eyes in PDT group. There was no significant difference in rest of the anatomical features between the groups. CONCLUSIONS: nMSL seems to be superior over PDT in improving visual and anatomical outcomes at 6 months and can be considered as a cheap alternative to PDT in treatment of CSCR. |
| Databáze: | OpenAIRE |
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