Further Support for Psychological Symptoms in Pediatric Celiac Disease

Autor: Laura B. Smith, Daniel Agardh, Kalle Kurppa
Rok vydání: 2019
Předmět:
Zdroj: Pediatrics. 144
ISSN: 1098-4275
0031-4005
Popis: * Abbreviations: CD — : celiac disease CDA — : celiac disease autoimmunity GFD — : gluten-free diet TGA — : tissue transglutaminase autoantibody Although celiac disease (CD) is a common condition in the pediatric population, it is underdiagnosed, and in the absence of significant gastrointestinal symptoms, screening is not common.1 This is particularly true in the United States, whereas in European countries, screening has been adopted more commonly.2 Past literature has suggested that untreated CD is accompanied by extraintestinal manifestations, such as anxiety and depression, and/or behavioral issues, such as aggression or oppositional behavior.3,4 In a 2017 report,5 we presented findings suggesting that even before diagnosis of CD or knowledge of their child’s celiac disease autoimmunity (CDA) status, parents of young children with CDA reported higher levels of anxiety, depression, aggression, and sleep problems on the Child Behavior Checklist than parents of children without CDA. Our results were mixed in that these relationships were found in 3.5-year-old children but not in 4.5-year-old children. Nonetheless, this provided preliminary support for … Address correspondence to Laura B. Smith, PhD, University of South Florida Diabetes Center, Morsani College of Medicine, University of South Florida, 13330 USF Laurel Dr, MDC 62, Tampa, FL 33612. E-mail: lsmith5{at}health.usf.edu
Databáze: OpenAIRE