Intravenous nitroglycerin for controlled cord traction in the management of retained placenta

Autor: Pattipa Suksopee, Suwimol Yimyam, Ladda Permpolprasert, Sukanya Suwanvichai, Shusee Visalyaputra, Japarath Prechapanich
Rok vydání: 2010
Předmět:
Zdroj: International Journal of Gynecology & Obstetrics. 112:103-106
ISSN: 0020-7292
DOI: 10.1016/j.ijgo.2010.08.021
Popis: Objective To determine the effect of 200 μg of intravenous nitroglycerin in the release of retained placenta by controlled cord traction. Methods In this randomized controlled study, 40 women with a placenta retained for 30 minutes received intravenously 200 μg of nitroglycerin or a normal saline solution before umbilical cord traction was initiated. The rates of successful removal of the retained placenta in the study (n = 20) and control (n = 20) groups were compared, as were blood pressure, pulse rate, blood loss, and adverse effects. Results The placenta was released in only 15% and 20% of the participants in the study and control group, respectively. The remainder of the participants required general anesthesia and manual removal of the retained placenta regardless of group assignation. Blood pressure fell in significantly more women in the study group, but there were no differences in estimated blood loss or minor adverse effects. Conclusion Intravenously administered nitroglycerin did not facilitate the release of retained placenta by umbilical cord traction. However, cord traction may be performed longer than 30 minutes to attempt releasing the placenta before operative manual removal is initiated.
Databáze: OpenAIRE