| Autor: |
Micaela Gliozzi, Roberta Macrì, Anna Rita Coppoletta, Vincenzo Musolino, Cristina Carresi, Miriam Scicchitano, Francesca Bosco, Lorenza Guarnieri, Antonio Cardamone, Stefano Ruga, Federica Scarano, Saverio Nucera, Rocco Mollace, Irene Bava, Rosamaria Caminiti, Maria Serra, Jessica Maiuolo, Ernesto Palma, Vincenzo Mollace |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Nutrients. 14(18) |
| ISSN: |
2072-6643 |
| Popis: |
Diabetes is a complex chronic disease, and among the affected patients, cardiovascular disease (CVD)is the most common cause of death. Consequently, the evidence for the cardiovascular benefit of glycaemic control may reduce long-term CVD rates. Over the years, multiple pharmacological approaches aimed at controlling blood glucose levels were unable to significantly reduce diabetes-related cardiovascular events. In this view, a therapeutic strategy combining SGLT2 inhibitors and plant extracts might represent a promising solution. Indeed, countering the main cardiometabolic risk factor using plant extracts could potentiate the cardioprotective action of SGLT2 inhibitors. This review highlights the main molecular mechanisms underlying these beneficial effects that could contribute to the better management of diabetic patients. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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