Ion release, fluoride charge of and adhesion of an orthodontic cement paste containing microcapsules
| Autor: | William A. Mchale, Brant D. Burbank, Stephen M. Gross, James Alan Doyle, Michael Slater, Alyssa Kava, Mark A. Latta |
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| Rok vydání: | 2015 |
| Předmět: |
Toothbrushing
business.product_category Materials science Orthodontic Brackets Drug Compounding Dentistry chemistry.chemical_element Dental Cements Capsules 02 engineering and technology Calcium Phosphates Ointments 03 medical and health sciences chemistry.chemical_compound Dental Materials Fluorides 0302 clinical medicine Drug Delivery Systems Animals Dental Enamel General Dentistry Tooth Demineralization Cement Ions Toothpaste Enamel paint business.industry Tooth surface 030206 dentistry Adhesion 021001 nanoscience & nanotechnology Phosphate Resin Cements Chemical engineering chemistry Glass Ionomer Cements visual_art Tooth Remineralization visual_art.visual_art_medium Cattle 0210 nano-technology business Fluoride Toothpastes |
| Zdroj: | Journal of dentistry. 45 |
| ISSN: | 1879-176X |
| Popis: | Objectives Dental materials capable of releasing calcium, phosphate and fluoride are of great interest for remineralization. Microencapsulated aqueous solutions of these ions in orthodontic cement demonstrate slow, sustained release by passive diffusion through a permeable membrane without the need for dissolution or etching of fillers. The potential to charge a dental material formulated with microencapsulated water with fluoride by toothbrushing with over the counter toothpaste and the effect of microcapsules on cement adhesion to enamel was determined. Methods Orthodontic cements that contained microcapsules with water and controls without microcapsules were brushed with over-the-counter toothpaste and fluoride release was measured. Adhesion measurements were performed loading orthodontic brackets to failure. Cements that contained microencapsulated solutions of 5.0 M Ca(NO3)2, 0.8 M NaF, 6.0 M K2HPO4 or a mixture of all three were prepared. Ion release profiles were measured as a function of time. Results A greater fluoride charge and re-release from toothbrushing was demonstrated compared to a control with no microcapsules. Adhesion of an orthodontic cement that contained microencapsulated remineralizing agents was 8.5 ± 2.5 MPa compared to the control without microcapsules which was of 8.3 ± 1.7 MPa. Sustained release of fluoride, calcium and phosphate ions from cement formulated with microencapsulated remineralizing agents was demonstrated. Conclusions Orthodontic cements with microcapsules show a release of bioavailable fluoride, calcium, and phosphate ions near the tooth surface while having the ability to charge with fluoride and not effect the adhesion of the material to enamel. Incorporation of microcapsules in dental materials is promising for promoting remineralization. |
| Databáze: | OpenAIRE |
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